A Postpartum Breast Cancer Diagnosis Reduces Survival in GermlineBRCApathogenic variant Carriers
Zhenzhen Zhang,
Shangyuan Ye,
Sarah M. Bernhardt
et al.
Abstract:IMPORTANCEIn young-onset breast cancer, a diagnosis within 5-10 years of childbirth associates with increased mortality. Women with germlineBRCA1/2pathogenic variants (PVs) are more likely to be diagnosed with breast cancer at younger ages, but the impact of childbirth on mortality is unknown.OBJECTIVEDetermine whether time between recent childbirth and breast cancer diagnosis impacts mortality among young-onset breast cancer patients with germlineBRCA1/2PVs.DESIGN, SETTING, AND PARTICIPANTSThis prospective co… Show more
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