A portable purification system for the rapid removal of microplastics from environmental samples

Early Predictor Tool of Disease Using Label-Free Liquid Biopsy-Based Platforms for Patient-Centric Healthcare

“…In recent years, microfluidic technology has been widely used in the field of particle detection [15] and biomedicine, such as with point of care testing [16][17][18][19], organs-on-achip [20,21], drug discovery [22], and liquid biopsy [23][24][25][26]. Cell sorting techniques can be divided into label-based and label-free technology [27,28].…”

“…To study the correlation between cluster parameters and patient prognosis, we analyzed clinical samples of liquid (blood) biopsy from cancer patients throughout their treatment (n = 22) (Table 1; no. [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][27][28][29][30][31]. Four samples with non-optimal optical images were not included in the analysis.…”

Removing microplastics from aquatic environments: A critical review

“…An MP concentrator (MPC) was designed and optimized, which could balance inertial lift forces and Dean drag forces in a fully enclosed system to concentrate MPs ≥19 μm. The MPC achieved more than 90% recovery of MPs from seawater samples and polypropylene (PP) food container extracts, and also obtained MPs counts (per gram wet sediment) for environmental ocean floor samples within the range (Polyurethane, Cis -polyisoprene, PS, PE, Nylon, Polyester, Ammonium polyacrylate, Alkyd resin, Melamine-formaldehyde resin, Anionic polymer (Hydraid 771), Adhesive (Tuff-Bond®)) previously achieved by filtration [ 60 ].…”

Label-free enrichment of human blast cells from whole blood for leukemia monitoring

“…Inertial focusing-based microfluidic chips effectively enrich particles of distinct physical attributes from samples in a label-free manner and are therefore promising tools in biomedical applications ( Chen et al., 2022 ; Khoo et al., 2019 ; Liao et al., 2021 ). This protocol demonstrates a unique procedure for enriching and detecting liquid biopsy blasts using a continuous flow BCB system.…”

“…Microfluidic chips based on inertial focusing can efficiently sort particles ( Chen et al., 2022 ). Similar applications capitalizing on the intrinsic mechanical and morphological properties of microparticles, including stiffness, size, and shape, have been reported for the label-free enrichment of heterogeneous cell suspensions in liquid biopsies ( Khoo et al., 2019 ; Liao et al., 2021 ).…”