A population study of the STR loci HUMLPL, HUMF13B, and HUMF13A01 in Hungary

Abstract

Allele frequencies of the three STR systems HUMLPL, HUMF13B, and HUMF13A01 were determined in a Hungarian population sample of 223 unrelated Caucasian individuals. All loci met Hardy-Weinberg expectations and there was no evidence for association of alleles among the three STR loci. In addition, little evidence was found for departures from expectations of independence between any of the three STR and other previously investigated microsatellite polymorphisms.

Population genetic data on four STR loci in a Hungarian Romany population

“…The Hungarian Romany allele frequency values (Table 1) for all loci were significantly different from a Central Hungarian population database [8,17] (P ≤ 10 -3 ). The combined forensic efficiency values observed in the Romany population sample [PD(4 loci) = 0.9995; MEC(4 loci) = 0.9125] were slightly smaller than those found in the Central Hungarian database.…”

“…Observed allele frequencies, homozygosities, and statistical data for the four STR loci in 135 unrelated Hungarian Romanies Allelic designation of this PCR fragment was confirmed by sequencing analysis determining a previously published [AAAT] 11 sequence motif[21] b These values are probability values c Statistics for the estimation of the locus specific genetic variability between the Baranya Romany and the Central Hungarian populations[8,17] …”

“…2). The US Caucasian [18], Polish [19] and Central Hungarian [8,17] populations formed the Caucasian group to which the Romanies are genetically related. The Chinese [20] and the African American [18] samples were clearly separated from the Caucasian group by showing long branches.…”

Polymorphism of LPL Locus in Japanese and Comparison of PCR Amplification Efficiency from Degraded DNA between LPL Locus and the D21S11

“…There are many reports on the frequency of the STR polymorphisms located at intron 6 of the lipoprotein lipase (LPL) locus [1][2][3][4][5][6][7][8][9][10][11][14][15][16][17][18] . Because the allelic sizes of this locus are comparatively small (111-135 bp), it is considered to be suitable for the detection of polymorphisms from highly degraded DNA.…”

Population data on the 11 STR loci in the Upper Silesia (Poland)

“…Allele distribution showed regional differences: at FESFPS locus for PomeraniaKujawy and North Poland, at D16S539 locus for South Poland, at F13A01 locus for North Poland (no high alleles met in this region) and at TH01 locus -Pomerania-Kujawy and WarmiaMazury were only homogeneous with the Upper Silesia. Comparison of allelic distribution between the Upper Silesia region and the nearest European neighbours (see Table 3): 10 STRs -Germany [16][17][18][19][20][21] and Hungary [22][23][24], 9 STRsRomania [25,26], 6 STRs -Slovenia [27] and only 3 STR markers -Czech Republic [28] and Russia [29] was also carried out. This paper follows the guidelines for publication of population data requested by Forensic Sci.…”