A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study

Abstract

Background. Chronic kidney disease (CKD) is a growing health problem worldwide that leads to end-stage kidney failure and cardiovascular complications. We aimed to determine the prevalence of CKD in Turkey, and to evaluate relationships between CKD and cardiovascular risk factors in a population-based survey.Methods. Medical data were collected through home visits and interviews. Serum creatinine, blood glucose, total cholesterol, triglycerides, HDL, LDL and uric acid were determined from 12-h fasting blood samples, and spot urine tests were performed for subjects who gave consent to laboratory evaluation.Results. A total of 10 872 participants were included in the study. The final analysis was performed on 10 748 subjects (mean age 40.5 ± 16.3 years; 55.7% women) and excluded 124 pregnant women. A low glomerular filtration rate (GFR) (< 60 mL/min/1.73 m2) was present in 5.2% of the subjects who were evaluated for GFR, while microalbuminuria and macroalbuminuria were observed in 10.2% and 2% of the subjects, respectively. The presence of CKD was assessed in subjects who gave consent for urinary albumin excretion measurement (n = 8765). The overall prevalence of CKD was 15.7%; it was higher in women than men (18.4% vs. 12.8%, P < 0.001) and increased with increasing age of the subjects. The prevalence of hypertension (32.7% in the general population), diabetes (12.7%), dyslipidaemia (76.3%), obesity (20.1%) and metabolic syndrome (31.3%) was significantly higher in subjects with CKD than subjects without CKD (P < 0.001 for all).Conclusions. The prevalence of CKD in Turkey is 15.7%. Cardiovascular risk factors were significantly more prevalent in CKD patients.

Türkiye’de Renal Replasman Tedavilerinin Güncel Durumu: Türk Nefroloji Derneği Kayıt Sistemi 2015 Yılı Özet Raporu

“…Registry kayıtlarımızın özellikle son yılına bakıldığında RRT gerektiren evre 5 kronik böbrek hastalığının (KBH) hem insidansında, hem de prevalansında artış eğilimi dikkat çekicidir. CREDIT ve TURDEP gibi epidemiyolojik çalışmalar son 10 yılda diyabetes mellitus oranının ülkemizde yaklaşık 2 kat arttığını göstermiştir (2,3). Registry kayıtlarımızda insidan hemodiyaliz olgularının etiyolojik dağılımlarına bakıldığında diyabetik hasta oranında %40'a çıktığını görmekteyiz.…”

Untitled

“…Derneğimizin önemli projelerinden birisi olan CREDIT çalışması, kronik böbrek hastalığının (KBH) ülkemiz açısından önemli bir halk sağlığı sorunu olduğunu ortaya koymuştur (2). Bu çalışma, 18 yaşın üzerindeki yetişkin popülasyonda KBH prevalansının %15,7 olduğunu, evre III-V arasındaki olgu oranının yaklaşık % 5,2 olduğunu, kadınlarda ve yaşlılarda etkilenmenin daha fazla olduğu göstermiştir.…”

Seroprevalance of the Hepatitis B and C in Patients with Chronic Kidney Disease without History of Renal Replacement Therapy

“…Chronic kidney disease (CKD) is an important public health problem leading to end stage renal disease and cardiovascular disease (1,2). Increase in the prevalence of diabetes and hypertension, prolongation of average life expectancy brings about a rise in the prevalence of CKD in our country, as in throughout the world (1)(2)(3)(4)(5).…”