A population-based study of the incidence and outcomes of diagnosed chronic kidney disease

Drey, Nicholas; Roderick, Paul; Mullee, Mark; Rogerson, Mary

doi:10.1016/s0272-6386(03)00916-8

Cited by 317 publications

(207 citation statements)

References 29 publications

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“…Control for the risk factors associated with CKD did not cancel completely the observed relationship between low SES (Area deprivation) and severe CKD. A previous study in UK also found the incidence of diagnosed/referred CKD to be greater in the more deprived areas, with poorer prognosis and decreased survival (11). A similar association has also been shown in national surveys in the US, with the relationship being more prevalent among the African-American groups (4 -10).…”

Section: Discussionsupporting

confidence: 66%

“…Socioeconomic differentials in health are widely recognized; individuals of lower socioeconomic status (SES) have a higher risk for mortality and morbidity compared with those of higher SES (2,3). Low SES is associated with increased risk for CKD from studies mostly based in the US population (4 -10) and a few in Europe (11,12). The association of CKD with SES in the various studies could be related to a higher number of socioeconomically disadvantaged individuals living in an area or the effect of the characteristics of the area (13).…”

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confidence: 99%

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Socioeconomic Status and Chronic Kidney Disease at Presentation to a Renal Service in the United Kingdom

Bello

Peters

Rigby

et al. 2008

Clinical Journal of the American Society of Nephrology

107

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Background and objectives: Low socioeconomic status (SES) is associated with both development and progression of chronic kidney disease (CKD). The impact of SES on severity of CKD at presentation to a renal service is less well known. This study investigated the relationship between SES and severity of CKD in a retrospective, cross-sectional analysis involving 1657 patients at the Sheffield Kidney Institute (Sheffield, UK).Design, setting, participants, & measurements: SES was assigned to each patient according to electoral ward of residence by postcode and ranked according to the corresponding British Index of Multiple Deprivation score, which comprises five deprivation quintiles (Q1, least deprived; Q5, most deprived). National Kidney Foundation Kidney Disease Outcomes Quality Initiative classification of CKD was used for stratification and analysis. Binary logistic regression analysis was applied for the association of variables/risk factors with CKD (lower GFR) at presentation.Results: The age-adjusted prevalence of diagnosed CKD at presentation by area of residence, across the five deprivation quintiles, per million population was Q1 ‫؍‬ 1495, Q2 ‫؍‬ 3530, Q3 ‫؍‬ 3398, Q4 ‫؍‬ 3989, and Q5 ‫؍‬ 19,599. Logistic regression models showed that living in the lowest SES quintile area (Q5) as compared with the highest SES (Q1) was associated with a greater risk for presenting with a lower estimated GFR, after adjustment for sociodemographic, lifestyle, and clinical variables.Conclusions: Low SES is related to severity of CKD at presentation. Further studies are needed to examine this issue across the various SES categories in the United Kingdom.

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Section: Discussionsupporting

confidence: 66%

mentioning

confidence: 99%

Socioeconomic Status and Chronic Kidney Disease at Presentation to a Renal Service in the United Kingdom

Bello

Peters

Rigby

et al. 2008

Clinical Journal of the American Society of Nephrology

107

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“…Previous studies have demonstrated that CKD increases the risks of cardiovascular morbidity and mortality (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13). The prevalence of CKD has been shown to be high in population studies (10% to 13%) (14 -16), and for CKD patients in the general population, the risk of death, particularly due to cardiovascular disease (CVD), is much higher than that of ESRD requiring renal replacement therapy (RRT) (12)(13).…”

mentioning

confidence: 99%

Impact of Age and Overt Proteinuria on Outcomes of Stage 3 to 5 Chronic Kidney Disease in a Referred Cohort

Obi

Kimura

Nagasawa

et al. 2010

Clinical Journal of the American Society of Nephrology

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Results: The median age of subjects was 67.0 years, and median follow-up was 3.2 years. Overt proteinuria was present in 57.0% of subjects. For stage 3, 4, and 5 CKD, cumulative mortality and probability of ESRD at 3 years was 9.5 and 6.5%, 11.2 and 27.8%, and 16.5 and 79.1%, respectively. Using proportional-hazards regression models, age was a determinant for death, whereas overt proteinuria was strongly associated with ESRD. Among stage 3 CKD patients older than 65 years without overt proteinuria, the incidence of death before renal replacement therapy (RRT) was 2.8/100 patient-years and none had ESRD. In patients with advanced CKD and overt proteinuria, the incidence of ESRD was substantially higher than that of death before RRT.Conclusions: Stratification by age, proteinuria level, and CKD stage could predict the competing outcomes of death before RRT and ESRD among CKD patients.

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“…(AIHW, 2009(AIHW, , 2016aCDC, 2017) In addition, socio-economic factors, such as income, education, and environmental factors may also affect the incidence, prevalence, and progression of CKD. Researchers in the United Kingdom (U.K.), the U.S., India, and Taiwan have found that having a low income has a considerable effect on the development of CKD compared to a high income (Drey, Roderick, Mullee, & Rogerson, 2003;Singh et al, 2013;Wen et al, 2008;White et al, 2008).…”

Section: Risk Factorsmentioning

confidence: 99%

Self-Management Program for People with Chronic Kidney Disease in Vietnam: A Pragmatic Randomised Controlled Trial

Nguyen¹

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A population-based study of the incidence and outcomes of diagnosed chronic kidney disease

Cited by 317 publications

References 29 publications

Socioeconomic Status and Chronic Kidney Disease at Presentation to a Renal Service in the United Kingdom

Socioeconomic Status and Chronic Kidney Disease at Presentation to a Renal Service in the United Kingdom

Impact of Age and Overt Proteinuria on Outcomes of Stage 3 to 5 Chronic Kidney Disease in a Referred Cohort

Self-Management Program for People with Chronic Kidney Disease in Vietnam: A Pragmatic Randomised Controlled Trial

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