Abstract:Introduction:
Mixed phenotype acute leukemia (MPAL) is exceeding rare, making up less than 1% of all acute leukemias1, 2. It harbors features of both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Most cases have features of B-ALL; those with features of T-ALL are particularly uncommon2. We treated a 74-year-old retired male with T/myeloid MPAL. His disease progressed through 7 lines of therapy over 18 months, resulting in significant cytopenias and toxicity. Given the refr… Show more
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