A population-based observational study of patients with pulmonary disorders in intensive care unit

Abstract

Background/Aims Only a few epidemiologic studies on the patients with pulmonary disorders admitted to intensive care unit exist. We investigated the characteristics and clinical outcomes of the patients with severe pulmonary disorders. Methods The sample cohort database of National Health Insurance Sharing Service from 2006 to 2015 was used. Operational definition of critically ill patients was adults who were either admitted to intensive care unit for at least 3 days or expired within first 2 days in the unit. The pulmonary disorder group comprised of critically ill patients with respiratory disease as the main diagnosis. Results Among the 997,173 patients, 12,983 (1.3%) in 383 intensive care units were categorized as critically ill. Patients in the pulmonary disorder group tended to have more comorbidities or disabilities. The length of hospital stay and duration of mechanical ventilation were longer in the pulmonary disorder group. Overall mortality and re-admission were higher in the pulmonary disorder group, with adjusted incidence rate ratios of 1.22 (95% confidence interval, 1.18 to 1.27) and 1.26 (95% confidence interval, 1.17 to 1.36), respectively. After adjustment by Cox regression, the pulmonary disorder group was an independent risk factor for in-hospital mortality. Conclusions In critically ill patients with pulmonary disorder, the use of healthcare resources was higher, and their clinical outcomes were significantly worse than the non-pulmonary disorder group.

The Impact of Mechanical Ventilation Duration on the Readmission to Intensive Care Unit: A Population-Based Observational Study

“…We analyzed 997,173 patients who were followed up from 2006 to 2015 with the informative data on readmission to ICU and post-discharge mortality. An MV event was identified by specific KCD-7 (7th revision of Korean Standard Classification of Diseases) codes in the claim database, which were considered highly accurate and exclusive ( Supplementary Table S1) 16 .…”

“…The eligibility criteria were as follows: (1) critically illness, (2) age ≥18 years, and (3) at least one MV code claim in ICU, regardless of the duration of MV. To exclude patients who required MV without critical illnesses, we only included patients who stayed for 3 or more days or those who expired in the ICU 16 . The patients were classified into five categories based on the duration of MV: MV for <7 days, 7-13 days, 14-20 days, 21-27 days, and ≥28 days.…”

Machine learning-based prediction of in-ICU mortality in pneumonia patients

“…Pneumonia is among the leading causes of death globally 1 , and each year, 0.1 million patients with pneumonia require intensive care unit (ICU) admission for mechanical ventilation (MV) 2 , 3 . Approximately half of the patients with respiratory failure in the ICU have pneumonia, and a quarter of them are re-admitted to the ICU 4 . Approximately 20–50% of patients with pneumonia who are admitted to the ICU die 4 – 7 .…”

“…Approximately half of the patients with respiratory failure in the ICU have pneumonia, and a quarter of them are re-admitted to the ICU 4 . Approximately 20–50% of patients with pneumonia who are admitted to the ICU die 4 – 7 . Clinical scoring systems to predict in-ICU mortality in critically ill patients have been introduced, but none of these have been specifically developed for patients admitted to the ICU with severe pneumonia.…”

Development and validation of a patient‐reported outcome measure for patients with chronic respiratory failure: The CRF‐PROM scale

“…Chronic respiratory failure (CRF) occurs in the advanced stages of many respiratory diseases, and it is associated with a high hospitalization rate and high mortality. 1 It continues to affect the quality of life of patients posthospitalization 2 in terms of physical and psychological factors as well as factors associated with social support, satisfaction with treatment and treatment compliance, among others.…”