A Polarized Light Microscopic Study to Comparatively evaluate Four Remineralizing Agents on Enamel viz CPP-ACPF, ReminPro, SHY-NM and Colgate Strong Teeth

Rajan, R. Sundara; Krishnan, Ramesh; Bhaskaran, Bibin; Kumar, Suresh V

doi:10.5005/jp-journals-10005-1281

Cited by 23 publications

(30 citation statements)

References 11 publications

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“…Evidence-based review and research studies on the calcium phosphate agent for prevention of tooth caries in children indicated that calcium and phosphate ion promote remineralization of early enamel caries,[37383940414243444546474849] which is in line with the results of this study; however, which type of calcium phosphate compound is the best remineralizing agent is still controversial. [4243444546474849]…”

Section: Discussionsupporting

confidence: 84%

The efficiency of child formula dentifrices containing different calcium and phosphate compounds on artificial enamel caries

Rirattanapong¹,

Vongsavan²,

Saengsirinavin³

et al. 2016

J Int Soc Prevent Communit Dent

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Objectives:Fluoride toothpaste has been extensively used to prevent dental caries. However, the risk of fluorosis is concerning, especially in young children. Calcium phosphate has been an effective remineralizing agent and is present in commercial dental products, with no risk of fluorosis to users. This in vitro study aimed to compare the effects of different calcium phosphate compounds and fluoride-containing dentifrices on artificial caries in primary teeth.Materials and Methods:Fifty sound primary incisors were coated with nail varnish, leaving two 1 mm2 windows on the labial surface before immersion in demineralizing solution for 96 hours to produce artificial enamel lesions. Subsequently, one window from each tooth was coated with nail varnish, and all 50 teeth were divided into five groups (n = 10); group A – deionized water; group B – casein phosphopeptide–amorphous calcium phosphate (CPP–ACP) paste (Tooth Mousse); group C – 500 ppm F (Colgate Spiderman®); group D – nonfluoridated toothpaste with triple calcium phosphate (Pureen®); and group E – tricalcium phosphate (TCP). Polarized light microscopy and Image-Pro® Plus software were used to evaluate lesions.Results:After a 7-day pH-cycle, mean lesion depths in groups A, B, C, D, and E had increased by 57.52 ± 10.66%, 33.28 ± 10.16%, 17.04 ± 4.76%, 32.51 ± 8.99%, and 21.76 ± 8.15%, respectively. All data were processed by the Statistical Package for the Social Sciences (version 16.0) software package. Comparison of percentage changes using one-way analysis of variance and Fisher's least squares difference tests at a 95% level of confidence demonstrated that group A was significantly different from the other groups (P < 0.001). Lesions in groups B and D had a significant lesion progression when compared with groups C and E.Conclusions:All toothpastes in this study had the potential to delay the demineralization progression of artificial enamel caries in primary teeth. The fluoride 500 ppm and TCP toothpastes were equal in the deceleration of enamel caries progression and better than CPP–ACP paste and TCP toothpaste.

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Section: Discussionsupporting

confidence: 84%

The efficiency of child formula dentifrices containing different calcium and phosphate compounds on artificial enamel caries

Rirattanapong¹,

Vongsavan²,

Saengsirinavin³

et al. 2016

J Int Soc Prevent Communit Dent

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“…In all of the in vitro studies [28][29][30][31][32][33][34][35]38 described above in which human teeth were used; all researchers demonstrated Novamin as an effective remineralizing agent as in our study, but there were some differences found between the studies, such as novamin which was found more effective in some studies 34,35 or less effective in other studies than dentrifices including fluoride and CPP-ACP. Some studies found no statistical differences between dentrifices in remineralizing potential as in our study.…”

Section: Discussionmentioning

confidence: 85%

“…In another in-vitro study, when they compared the remineralizing potential of four commercially available products namely SHY-NM (Novamin), GC Tooth Mousse Plus (CPP-ACP and 900 ppm fluoride), ReminPro (hydroxyapatite 1450 ppm fluoride and Xylitol) and Colgate strong teeth (1000 ppm fluorid) on demineralized human teeth, SHY-NM had the most remineralizing potential followed by ReminPro, GC Tooth Mousse Plus and fluoridated toothpaste. 30 Mettu et al 31 reported that CPP-ACP increases enamel surface hardness. In a study, the CCP-ACP paste showed remineralizationinducing effect on artificially induced initial caries lesions.…”

Section: Discussionmentioning

confidence: 99%

Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study

Abbasoğlu

Bıçak

Dergin

et al. 2019

Cumhuriyet Dental Journal

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Objectives: New bio-active glass containing toothpaste (NovaMin) is one of the most effective cariostatic products when used as a daily application the aim of this in-vitro study is to evaluate the influence of NovaMin on enamel remineralization. Materials and Methods: Twenty-eight sound human enamel samples were randomly divided into four groups (A-D) each having seven samples as follows: A (Novamin), B (1450 ppm NaF and Novamin), C (CPP-ACP), D (1450ppm NaF). After inducing caries-like lesions, each group was maintained daily for demineralizationremineralization cycle for seven days. During this cycle, samples were treated by the selected toothpaste for each group. Enamel mineral loss was assessed by surface microhardness. Surface enamel microhardness was determined on the enamel blocks. Non-parametric Kruskar-Wallis test compares the amount of surface microhardness recovery (SMHR%) across four different toothpastes. Results: PLM data revealed a mineral precipitation band on the surface layer of all toothpastes; however, when compared to treated lesions, no statistically differences among the groups (p>0.05) were found. Conclusions: NovaMin containing dentifrice has similar remineralization potential on carious-like lesions when compared to fluoride containing dentifrices.

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“…This is in agreement with a study by Marchetti E et al, which demonstrated a continuous increase in mineral gain and the return of the microhardness values to near baseline level when a HA based cream was used after bleaching procedure 18 . In several studies this has been attributed to the filling of the irregular enamel of the bleached surface with hydroxyapatite (HA) crystals and the formation of fluorapatite (FA) due to the high fluoride content of 1450 ppm fluoride, which is 61% higher than other brands available [900 ppm in CPP-ACPF & 950 ppm in β-TCP] 19,20,21 .…”

Section: Methodsmentioning

confidence: 99%

Comparative Evaluation of the Effect of Various Remineralizing Agents on Bleached Enamel Surface: An in Vitro Study

Thakur¹,

Devadiga²,

Hegde³

2016

J. Pharm. Sci. Innov.

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The aim of this study is to comparative evaluate the remineralization potential of various newer remineralizing agents such as Fluoride enriched Casein Phospho-peptide Amorphous calcium phosphate, Beta Tri-calcium Phosphate and Hydroxyapatite based cream on bleached enamel surface using Surface hardness test. 40 freshly extracted intact human premolars extracted for orthodontic purpose were used to prepare 75 enamel sections from the buccal and palatal surfaces of t`he teeth. The teeth were divided into 5 groups of 15 specimens and subjected to surface treatment as follows: Grp 1: Intact tooth (Control group) -No Surface treatment, Grp 2: Bleaching with 35% Hydrogen peroxide (Pola-office), Group 3: CPP-ACPF (GC Tooth Mousse plus, GC Corp) for two applications, 4 mins each for 14 days, Group 4: β-TCP (3M ESPE ClinPro) for 4 min for 14 days, Group 5: Hydroxyapatite based cream (ReminPro, VOCO) for 30 minutes for 10 days. All the specimens were stored in artificial saliva in the intervals and throughout the study. The specimens were subjected to qualitative and quantitative evaluation using Surface Hardness test for Vickers Hardness Number. Enamel specimens treated with bleaching agent (Pola Office) showed a decrease in microhardness which was statistically significant when compared with unbleached enamel [Grp1]. Among the remineralising agents tested in the study Hydroxyapatite based cream was found to be marginally more effective then the CPP-ACPF and β-TCP which was not statistically different.

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A Polarized Light Microscopic Study to Comparatively evaluate Four Remineralizing Agents on Enamel viz CPP-ACPF, ReminPro, SHY-NM and Colgate Strong Teeth

Cited by 23 publications

References 11 publications

The efficiency of child formula dentifrices containing different calcium and phosphate compounds on artificial enamel caries

The efficiency of child formula dentifrices containing different calcium and phosphate compounds on artificial enamel caries

Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study

Comparative Evaluation of the Effect of Various Remineralizing Agents on Bleached Enamel Surface: An in Vitro Study

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