A plasmonic fluorescent ratiometric temperature sensor for self-limiting hyperthermic applications utilizing FRET enhancement in the plasmonic field

George, Sharon A.; Palantavida, Shajesh

doi:10.1039/d3an00800b

Cited by 1 publication

(1 citation statement)

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“…These properties of diamonds make them very attractive for biomedical applications. For instance, fluorescent nanodiamondgold/silver nanoparticles were used for cell labeling and photothermal therapy [7,8]. In [9], laser-synthesized nanodiamonds coated with polydopamine exhibited strong photothermal properties combined with fluorescent imaging.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Core/Shell Diamond Nanoparticles Combining Unique Thermal and Light Properties for Future Biological Applications

Grudinkin,

Bogdanov,

Tolmachev

et al. 2023

Nanomaterials

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We report the development of multifunctional core/shell chemical vapor deposition diamond nanoparticles for the local photoinduced hyperthermia, thermometry, and fluorescent imaging. The diamond core heavily doped with boron is heated due to absorbed laser radiation and in turn heats the shell of a thin transparent diamond layer with embedded negatively charged SiV color centers emitting intense and narrowband zero-phonon lines with a temperature-dependent wavelength near 738 nm. The heating of the core/shell diamond nanoparticle is indicated by the temperature-induced spectral shift in the intensive zero-phonon line of the SiV color centers embedded in the diamond shell. The temperature of the core/shell diamond particles can be precisely manipulated by the power of the incident light. At laser power safe for biological systems, the photoinduced temperature of the core/shell diamond nanoparticles is high enough to be used for hyperthermia therapy and local nanothermometry, while the high zero-phonon line intensity of the SiV color centers allows for the fluorescent imaging of treated areas.

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Section: Introductionmentioning

confidence: 99%

Multifunctional Core/Shell Diamond Nanoparticles Combining Unique Thermal and Light Properties for Future Biological Applications

Grudinkin,

Bogdanov,

Tolmachev

et al. 2023

Nanomaterials

View full text Add to dashboard Cite

show abstract

A plasmonic fluorescent ratiometric temperature sensor for self-limiting hyperthermic applications utilizing FRET enhancement in the plasmonic field

Abstract: Nanoparticle mediated photo induced hyperthermia holds much promise as a therapeutic solution for the management of diseases like cancer. The conventional methods of temperature measurements do not measure the actual...

Cited by 1 publication

References 52 publications

Multifunctional Core/Shell Diamond Nanoparticles Combining Unique Thermal and Light Properties for Future Biological Applications

Multifunctional Core/Shell Diamond Nanoparticles Combining Unique Thermal and Light Properties for Future Biological Applications

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