A plant-based dietary score and attention deficit/hyperactivity disorder in Iranian children: A case-control study

Darand, Mina; Hassanizadeh, Shirin; Martami, Fahime; Shareghfarid, Elham; Hosseinpour-Niazi, Somayeh; Hosseinzadeh, Mahdieh

doi:10.1016/j.jad.2022.06.006

Cited by 2 publications

(5 citation statements)

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“…One explanation might be that the calculation of PDI (18 food groups) might be more informative, inclusive and comprehensive for assessing children's diet, which makes children's PDI diet score more sensitive to children's mental health outcomes. For instance, a case-control study in 345 Iranian children suggested that PDI diet was associated with a lower risk of attention deficit/hyperactivity disorder (ADHD) 53 . However, there are still very limited studies on children, therefore, more studies are needed to explain the associations between PDI and children' mental health.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, applying dietary scores to adolescents and children needs to be investigated further, as young people require specific nutrients for healthy growth. However, some studies have applied these dietary scores in children, including PDI, DASH and Mediterranean dietary scores 53,58,59 . Additionally, we performed a sensitivity analysis to try and minimise this effect.…”

Section: Discussionmentioning

confidence: 99%

“…For instance, a case-control study in 345 Iranian children suggested that PDI diet was associated with a lower risk of attention deficit/hyperactivity disorder. 53 However, there are still very limited studies on children, therefore, more studies are needed to explain the associations between PDI and children' mental health.…”

Section: Food and Function Papermentioning

confidence: 99%

“…However, some studies have applied these dietary scores in children, including PDI, DASH and Mediterranean dietary scores. 53,58,59 Additionally, we performed a sensitivity analysis to try and minimise this effect. Finally, due to the cross-sectional nature of the study, causality could not be inferred, and further longitudinal studies are needed to address the exact relationship between dietary patterns and mood.…”

Section: Food and Function Papermentioning

confidence: 99%

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Plant-based dietary patterns and their association with mood in healthy individuals

et al. 2023

Food Funct.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Food and Function Papermentioning

confidence: 99%

Section: Food and Function Papermentioning

confidence: 99%

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Plant-based dietary patterns and their association with mood in healthy individuals

et al. 2023

Food Funct.

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“…The effects of the Vegan Diet on ADHD or specific ADHD symptoms, such as inattention, hyperactivity, and impulsivity, have not been studied yet. However, there are some clinical studies [ 72 ].…”

Section: Discussionmentioning

confidence: 99%

Understanding the ADHD-Gut Axis by Metabolic Network Analysis

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2023

Metabolites

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Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder diagnosed with hyperactivity, impulsivity, and a lack of attention inconsistent with the patient’s development level. The fact that people with ADHD frequently experience gastrointestinal (GI) dysfunction highlights the possibility that the gut microbiome may play a role in this condition. The proposed research aims to determine a biomarker for ADHD by reconstructing a model of the gut-microbial community. Genome-scale metabolic models (GEM) considering the relationship between gene-protein-reaction associations are used to simulate metabolic activities in organisms of gut. The production rates of dopamine and serotonin precursors and the key short chain fatty acids which affect the health status are determined under three diets (Western, Atkins, Vegan) and compared with those of healthy people. Elasticities are calculated to understand the sensitivity of exchange fluxes to changes in diet and bacterial abundance at the species level. The presence of Bacillota (genus Coprococcus and Subdoligranulum), Actinobacteria (genus Collinsella), Bacteroidetes (genus Bacteroides), Bacillota (genus Coprococcus and Subdoligranulum), and Bacteroidota (genus Alistipes) may be possible gut microbiota indicators of ADHD. This type of modeling approach taking microbial genome-environment interactions into account helps us understand the gastrointestinal mechanisms behind ADHD, and establish a path to improve the quality of life of ADHD patients.

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A plant-based dietary score and attention deficit/hyperactivity disorder in Iranian children: A case-control study

Cited by 2 publications

References 42 publications

Plant-based dietary patterns and their association with mood in healthy individuals

Plant-based dietary patterns and their association with mood in healthy individuals

Understanding the ADHD-Gut Axis by Metabolic Network Analysis

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