A plant antifungal product from Melianthus comosus (Melianthaceae) leaf extracts

Eloff, Jacobus Nicolaas; Angeh, I.; McGaw, L.J.

doi:10.1055/s-2006-949793

Cited by 7 publications

(4 citation statements)

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“…The challenge from this point appears to provide products for the herbal medicine industry based on extracts where the activity has been enhanced by removing inactive compounds as has been done by Zishiri (2005) and also in another application by Irene Angeh (Angeh, 2006;Eloff et al, 2006). Research into the mechanism of synergy could also provide very interesting data.…”

Section: Discussionmentioning

confidence: 99%

The biological activity and chemistry of the southern African Combretaceae

Eloff

Katerere

McGaw

2008

Journal of Ethnopharmacology

167

122

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Section: Discussionmentioning

confidence: 99%

The biological activity and chemistry of the southern African Combretaceae

Eloff

Katerere

McGaw

2008

Journal of Ethnopharmacology

167

122

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“…The extraction yield in acetone of the two plant materials were 4.34 % w/w (C. citratus) and 4.68 % w/w (O. gratissimum). The choice of acetone was due to its high solvent strength, its intermediate polarity as well as good selectivity for extracting bioactive metabolites [10,11]. The anthelmintic profiles of the extracts are shown in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Anthelmintic activity of Ocimum gratissimum and Cymbopogon citratus leaf extracts against Haemonchus placei adult worm

Aderibigbe¹

2020

J. Pharm Bio.

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Medicinal plants are promising, as source of alternative solution to the problem of parasitic helminth infections that hamper the sustainable supply of products from farm animals. Ocimum gratissimum and Cymbopogon citratus leaves are commonly used internally to treat worms, relieve abdominal pains and stomach ache. This study, therefore, evaluated their leaf extracts for anthelmintic activity against Haemonchus placei worm from cattle; the most active extract being subjected to phytochemical analysis. The extracts, obtained by maceration using acetone, were evaluated for anthelmintic activity by exposing adult H. placei to a range of concentrations (5-60 mg/mL) for 3 hours and then counting the number of confirmed dead worms. Anthelmintic activity data were fitted to a non-linear regression equation (Log [extract] vs. response; variable slope) to produce best-fit sigmoidal curves from which LC50 values were computed. The best-fit LC50 values, found to be significantly different (alpha < 0.0001), were 17.70 mg/mL and 56.04 mg/mL for C. citratus and O. gratissimum, respectively, suggesting that C. citratus is three times more potent than O. gratissimum. Phytochemical analysis of C. citratus indicated the presence of alkaloids, tannins, steroids, saponins, terpenoids and flavonoids. Cymbopogon citratus could be useful as an anthelmintic phytomedicine against livestock parasitic helminths. Keywords: Anthelmintic; Haemonchus placei; Motility assay; Ocimum gratissimum; Cymbopogon citratus

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“…Según Eloff et al (2017), una variable importante para obtener mayor actividad antifúngica es la polaridad de los extractos, con polaridad intermedia tenemos mayor capacidad antifúngica que con extractos muy polares o completamente apolares, ya que de eso depende la cantidad y/o tipo de compuestos extraídos como taninos, fenoles, flavonoides, etc. (Torgbo et al, 2022;Lourenço et al, 2019).…”

Section: Actividad Antifúngicaunclassified

In vitro antifungal activity of blueberry branches/leaves and avocado seed extracts against Botrytis sp.

Flores-Bedregal,

Puelles-Román,

Mendoza-Moncada

et al. 2023

Agroind. sci.

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Currently, the search for eco-friendly products has become more intensive, guiding the agro-industry towards more sustainable practices. Obtaining bioactive compounds with antifungal activity represents a viable source of fungicides for postharvest use, since up to now there is still a high demand for chemical fungicides in the industry. The effect of two aqueous extracts of acetone origin obtained from blueberry branches and leaves (mixture) and avocado seed was evaluated. This plant material is part of agro-industrial waste from the production process of the company Camposol S.A. To determine the concentration of polyphenols, the Folin Ciocalteu method was used and for the antioxidant capacity, the DPPH radical method. The tentative identification of compounds present in each extract was performed using UHPLC-DAD-ESI/MS. The acetone extracts were dried and re-suspended in water. Three concentrations (5, 25 and 50 mg/mL) were used on the inhibition of spore germination and mycelial growth of Botrytis sp. 55% inhibition of spores was obtained after 24 h of incubation and 19% inhibition in growth mycelial at 7 days of incubation. This research contributes to the valorization of by-products, giving them added value, encouraging the development and implementation of new products based on plant material with important bioactive potential for the emerging sector of Agro-industry.

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A plant antifungal product from Melianthus comosus (Melianthaceae) leaf extracts

Cited by 7 publications

References 0 publications

The biological activity and chemistry of the southern African Combretaceae

The biological activity and chemistry of the southern African Combretaceae

Anthelmintic activity of <i>Ocimum gratissimum</i> and <i>Cymbopogon citratus</i> leaf extracts against <i>Haemonchus placei</i> adult worm

In vitro antifungal activity of blueberry branches/leaves and avocado seed extracts against Botrytis sp.

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