A pilot trial of cognitive behavioural therapy for interpersonal sensitivity in individuals with persecutory delusions

Bell, Victoria; Freeman, Daniel

doi:10.1016/j.jbtep.2014.06.001

Cited by 36 publications

(34 citation statements)

References 29 publications

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“…A similar pattern was evident in ARMS individuals, who reported more intense psychotic experiences in response to experiences of outsider status following exposure to high levels of sexual abuse. We may therefore speculate that one specific pathway for the impact of childhood sexual abuse on psychosis may be via heightened interpersonal sensitivity by creating an enduring sense of feeling vulnerable in the presence of others (Bell & Freeman, 2014), which has been previously reported to be a relevant psychological mechanism in individuals with a psychotic disorder and ARMS (Bell & Freeman, 2014). What is more, our findings extended beyond interpersonal sensitivity and also involved sensitivity to wider adverse socio-environmental contexts in daily life (i.e.…”

Section: Discussionmentioning

confidence: 99%

Psychological processes underlying the association between childhood trauma and psychosis in daily life: an experience sampling study

et al. 2016

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BackgroundEvidence has accumulated that implicates childhood trauma in the aetiology of psychosis, but our understanding of the putative psychological processes and mechanisms through which childhood trauma impacts on individuals and contributes to the development of psychosis remains limited. We aimed to investigate whether stress sensitivity and threat anticipation underlie the association between childhood abuse and psychosis.MethodWe used the Experience Sampling Method to measure stress, threat anticipation, negative affect, and psychotic experiences in 50 first-episode psychosis (FEP) patients, 44 At-Risk Mental State (ARMS) participants, and 52 controls. Childhood abuse was assessed using the Childhood Trauma Questionnaire.ResultsAssociations of minor socio-environmental stress in daily life with negative affect and psychotic experiences were modified by sexual abuse and group (all pFWE < 0.05). While there was strong evidence that these associations were greater in FEP exposed to high levels of sexual abuse, and some evidence of greater associations in ARMS exposed to high levels of sexual abuse, controls exposed to high levels of sexual abuse were more resilient and reported less intense negative emotional reactions to socio-environmental stress. A similar pattern was evident for threat anticipation.ConclusionsElevated sensitivity and lack of resilience to socio-environmental stress and enhanced threat anticipation in daily life may be important psychological processes underlying the association between childhood sexual abuse and psychosis.

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Section: Discussionmentioning

confidence: 99%

Psychological processes underlying the association between childhood trauma and psychosis in daily life: an experience sampling study

et al. 2016

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“…On the other hand, difficulties in communication and relations with the peer group could exacerbate the sensitivity to interpersonal interactions and feelings of having a fragile core-self. Assessing levels of interpersonal sensitivity and planning targeted psychotherapeutic interventions (Nelson et al, 2009;Bell and Freeman, 2014) in order to struggle potential difficulties in interpersonal relationships may be a therapeutic action to stop the afore-mentioned vicious cycle and to avoid a poor long-term outcome (Nelson et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Interpersonal sensitivity and functioning impairment in youth at ultra-high risk for psychosis

Masillo

Valmaggia

Saba

et al. 2015

Eur Child Adolesc Psychiatry

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“…And negative cognitions about the self and others will be one route via which adverse events lead to paranoia [29, 59, 60]. One promising more refined specification is interpersonal sensitivity, defined as ‘feeling vulnerable in the presence of others due to the expectation of criticism or rejection’ [61]. Paranoid ideation can be considered as an extension of such concerns.…”

Section: Interpersonal Sensitivitymentioning

confidence: 99%

“…A recent pilot study has provided an initial test of the effect on persecutory delusions of intervening on interpersonal sensitivity [61]. Eleven patients with persistent persecutory delusions and reporting interpersonal sensitivity took part.…”

Section: Interpersonal Sensitivitymentioning

confidence: 99%

Advances in understanding and treating persecutory delusions: a review

Freeman

Garety

2014

Soc Psychiatry Psychiatr Epidemiol

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307

261

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PurposePersecutory delusions are a central psychotic experience, at the severe end of a paranoia spectrum in the general population. The aim of the review is to provide an introduction to the understanding of persecutory delusions, highlight key putative causal factors that have the potential to be translated into efficacious treatment, and indicate future research directions.MethodsA narrative literature review was undertaken to highlight the main recent areas of empirical study concerning non-clinical and clinical paranoia.ResultsSix main proximal causal factors are identified: a worry thinking style, negative beliefs about the self, interpersonal sensitivity, sleep disturbance, anomalous internal experience, and reasoning biases. Each has plausible mechanistic links to the occurrence of paranoia. These causal factors may be influenced by a number of social circumstances, including adverse events, illicit drug use, and urban environments.ConclusionsThere have been numerous replicated empirical findings leading to a significant advance in the understanding of persecutory delusions, now beginning to be translated into cognitive treatments. The first trials specifically focussed on patients who have persecutory delusions in the context of psychotic diagnoses are occurring. Initial evidence of efficacy is very promising.

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A pilot trial of cognitive behavioural therapy for interpersonal sensitivity in individuals with persecutory delusions

Cited by 36 publications

References 29 publications

Psychological processes underlying the association between childhood trauma and psychosis in daily life: an experience sampling study

Psychological processes underlying the association between childhood trauma and psychosis in daily life: an experience sampling study

Interpersonal sensitivity and functioning impairment in youth at ultra-high risk for psychosis

Advances in understanding and treating persecutory delusions: a review

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