A Pilot Study of the Clinical Frailty Scale to Predict Frailty Transition and Readmission in Older Patients in Vietnam

Nguyen, Tan Van; Ly, Thuy Thanh; Nguyen, Tu Ngoc

doi:10.3390/ijerph17051582

Cited by 5 publications

(5 citation statements)

References 19 publications

(38 reference statements)

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“…Therefore, this study aimed to explore this discrepancy, by investigating whether there is a significant correlation between MetS and frailty in older people in Vietnam-a country that is situated in the Southeast Asian region. Previous studies in Vietnam have shown that the prevalence of frailty was 21.7% in community-dwelling older people [16] and 32-55% in older hospitalized patients [17,18]. We hypothesized that in older people, MetS is associated with increased risk of acquiring frailty.…”

Section: Introductionmentioning

confidence: 94%

Examine the Association between Metabolic Syndrome and Frailty in an Older Asian Population

Dao

Nguyen

et al. 2022

Diabetology

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Background: There has been evidence that metabolic syndrome (MetS) may increase the risk of frailty. However, there is limited evidence on this association in Asian populations. Aims: This study aims to identify the association between MetS and frailty in older people in Vietnam. Methods: This is a cross-sectional analysis of a dataset that was obtained from an observational study on frailty and sarcopenia in patients aged ≥60 at a geriatric hospital in Vietnam. Frailty was defined by the frailty phenotype. The participants were defined as having MetS if they had ≥3 out of 5 criteria from the definition of the National Cholesterol Education Program (NCEP) Adults Treatment Panel (ATP) III. Multiple logistic regression models were performed to estimate the risk of having frailty in patients with MetS. Results: Of the 669 participants (mean age 71, 60.2% female), 62.3% had MetS and 39.0% were frail. The prevalence of frailty was 42.2% in participants with MetS and 33.7% in participants without MetS (p = 0.029). On the logistic regression models, MetS was associated with an increased likelihood of being frail (adjusted OR 1.52, 95%CI 1.01–2.28), allowing for age, sex, education, nutritional status, history of hospitalization, and chronic diseases. Conclusion: There was a significant association between MetS and frailty in this population. Further longitudinal studies are required to confirm this association.

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Section: Introductionmentioning

confidence: 94%

Examine the Association between Metabolic Syndrome and Frailty in an Older Asian Population

Dao

Nguyen

et al. 2022

Diabetology

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“…CFS was developed to identify patients at high risk of adverse events (e.g., pressure ulcers and malnutrition) in a standardized way to enable patient-centered care [37,38]. The scale can be dichotomized, where CFS 1-4 correspond to non-frail ("robust") and CFS 5-9 to frail [26][27][28]. CFS 9 means that the patient is terminally ill.…”

Section: Clinical Frailty Scalementioning

confidence: 99%

“…However, a majority of the studies have been conducted on patients referred for GFR measurement, patients connected to nephrology clinics or on large study cohorts in an outpatient setting. Frail elderly people represent the majority of patients in geriatric wards [25][26][27]. Increasing frailty predisposes risks for inpatient care [26,28].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Creatinine and Cystatin C to Estimate Renal Function in Geriatric and Frail Patients

Dahlén¹,

Björkhem‐Bergman

2022

Life

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The aim of this study was to compare estimated glomerular filtration rate (eGFR) with creatinine (eGFRcrea) and cystatin C (eGFRcys) in geriatric and frail patients. A retrospective, cross-sectional study was performed at a geriatric clinic in Stockholm (n = 95). The revised Lund–Malmö equation was used to calculate eGFRcrea and the Caucasian-Asian-Pediatric-Adult (CAPA) equation was used for eGFRcys. The absolute mean percentage difference between eGFRcrea and eGFRcys was used as a surrogate measure for accuracy in eGFR. Other outcome measures were consistency expressed in Lin’s concordance correlation coefficient and the proportion of consistent staging of renal failure. Subgroup analyses were performed with regard to frailty (according to Clinical Frailty Scale) and age. eGFRcys estimated lower GFR than eGFRcrea across the entire study population as well as in all subgroups (p < 0.05). Difference between the estimates increased with increasing frailty (r2 = 0.15, p < 0.01), but was not significantly affected by age (r2 = 0.004, p = 0.55). In conclusion, eGFRcys was significantly lower compared to eGFRcrea in geriatric and frail patients. Moreover, frailty had greater impact than age on the accuracy of eGFR. However, this study cannot determine if any of the estimates are preferable over the other in this patient group.

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“…Previous studies in Vietnam showed that the prevalence of frailty was 21.7% in community-dwelling older people 16 , and 32%-55% in older hospitalised patients. 17,18 We hypothesised that in older people, MetS is associated with increased risk of acquiring frailty.…”

Section: Introductionmentioning

confidence: 99%

Examine the Association between Metabolic Syndrome and Frailty in an Older Asian Population

Dao¹,

Nguyen²,

Vu³

et al. 2021

Preprint

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Background: There has been evidence that metabolic syndrome (MetS) may increase the risk of frailty. However, there is limited evidence on this association in Asian populations. Aims: This study aims to identify the association between MetS and frailty in older people in Vietnam. Methods: This is a cross-sectional analysis of a dataset obtained from an observational study on frailty and sarcopenia in patients aged ≥60 at a geriatric hospital in Vietnam. Frailty was defined by the frailty phenotype. Participants were defined as having MetS if they had ≥3 out of 5 criteria from the definition of the National Cholesterol Education Program (NCEP) Adults Treatment Panel (ATP) III. Multiple logistic regression models were performed to estimate the risk of having frailty in patients with MetS. Results: There were 669 participants (mean age 71, 60.2% female), 62.3% had MetS and 39.0% was frail. The prevalence of frailty was 42.2% in participants with MetS, 33.7% in participants without MetS (p=0.029). On logistic regression models, MetS was associated with increased likelihood of being frail (adjusted OR 1.52, 95%CI 1.01-2.28), allowing for age, sex, education, nutritional status, history of hospitalisation and chronic diseases. Conclusion: There was a significant association between MetS and frailty in this population. Further longitudinal studies are required to confirm this association.

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A Pilot Study of the Clinical Frailty Scale to Predict Frailty Transition and Readmission in Older Patients in Vietnam

Cited by 5 publications

References 19 publications

Examine the Association between Metabolic Syndrome and Frailty in an Older Asian Population

Examine the Association between Metabolic Syndrome and Frailty in an Older Asian Population

Comparison of Creatinine and Cystatin C to Estimate Renal Function in Geriatric and Frail Patients

Examine the Association between Metabolic Syndrome and Frailty in an Older Asian Population

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