A Pilot Study Evaluating the Effect of Mindfulness-Based Stress Reduction on Psychological Status, Physical Status, Salivary Cortisol, and Interleukin-6 Among Advanced-Stage Cancer Patients and Their Caregivers

Lengacher, Cecile A.; Kip, Kevin E.; Barta, Michelle; Post-White, Janice; Jacobsen, Paul B.; Groër, Maureen; Lehman, Brandy; Moscoso, Manolete S.; Kadel, Rajendra; Le, Nancy; Loftus, Loretta; Stevens, Craig; Malafa, Mokenge P.; Shelton, Melissa M.

doi:10.1177/0898010111435949

Cited by 127 publications

(182 citation statements)

References 59 publications

(80 reference statements)

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“…We expected to find this greater improvement in health in caregivers, taking into account that they are a chronically stressed population, and the MBP program is primarily focused on stress management. This hypothesis is in line with the results of a previous research in which this type of program has been used with caregivers (Lengacher et al 2012;Minor et al 2006).…”

Section: Introductionsupporting

confidence: 91%

“…With regard to pro-inflammatory biomarkers, a progressive reduction in Th1 cytokine levels was found over 1 year of participation in this type of intervention (Carlson et al 2007). In caregivers of people with cancer, the participation in a mindfulness-based stress reduction (MBSR) program reduced cortisol and interleukin-6 levels (Lengacher et al 2012).…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the efficacy of the program for improving health and negative mood in each group was analyzed comparing caregivers and noncaregivers. We hypothesized that both caregivers and noncaregivers would show better mood (less anxiety, negative mood, and feelings of anger) (Lykins and Baer 2009), as well as lower afternoon cortisol levels (Lengacher et al 2012), after each evaluated session of MBP. In addition, we hypothesized that the health status of caregivers and non-caregivers would improve after the intervention program, together with an adjustment in morning cortisol levels (Bränström et al 2013).…”

Section: Introductionmentioning

confidence: 99%

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A Mindfulness-Based Program Improves Health in Caregivers of People with Autism Spectrum Disorder: a Pilot Study

et al. 2014

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Mindfulness-based interventions have demonstrated to be effective in reducing stress and health complaints in clinical populations. However, to our knowledge, biological health markers have not been used in studies of the effectiveness of mindfulness programs in caregivers of people with autism spectrum disorders (ASDs). This study aimed to assess the effects of a mindfulness intervention on mood disturbances and health complaints in this population compared with non-caregivers. The design of the study was quasiexperimental, with repeated measures. Self-reported health, cortisol awakening response (CAR), and afternoon cortisol levels before and after a mindfulness session were assessed at the beginning, middle, and end of the intervention. There was a significant reduction in mood disturbances and afternoon cortisol levels during the sessions in all participants, with the reductions being more pronounced in caregivers. Moreover, all participants showed fewer depressive and somatic symptoms at the end of the program, with an improvement in their self-perceived general health. Nevertheless, the CAR levels had not changed significantly after the program. Overall, these results indicate that mindfulness group therapy could be effective for reducing health complaints and reinforce the validity of these programs for caregivers.

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Section: Introductionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Mindfulness-Based Program Improves Health in Caregivers of People with Autism Spectrum Disorder: a Pilot Study

et al. 2014

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“…With regards to family caregivers and other family members, high levels of stress, which are associated with reduced caregiver QoL [31], and decreased mental health-related QoL [32] have been documented. Of note, in diseases such as advanced cancers and asthma, attempts to lower stress and improve QoL and emotional function by structured multidisciplinary interventions have shown promising results both for patients [33][34][35][36] and carers [34]. Considering these data and the findings of this survey, it is the opinion of the Pulmonary Hypertension Associations of Europe, the UK and the USA that a number of initiatives are required to ensure there is a comprehensive standard of care in the management of PAH.…”

Section: Implications For the Future Management Of Pahmentioning

confidence: 86%

Understanding the impact of pulmonary arterial hypertension on patients' and carers' lives

Guillevin¹,

Armstrong²,

Aldrighetti³

et al. 2013

European Respiratory Review

128

214

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Pulmonary arterial hypertension (PAH) is a rare, debilitating and rapidly progressive disease. Although there have been important medical advances in PAH management, the search for a cure continues. Despite an increased understanding of the disease, data on the wider effect of PAH on patients and carers, beyond the clinical symptoms, are still limited. In order to explore this, a large-scale international survey investigated four key areas affected by PAH (physical and practical, emotional, social, and information needs) and provides new insight into patients' and carers' experiences of living with the disease. The results from the survey highlight not only the limited ability of patients to carry out everyday tasks, but also the financial impact and social isolation experienced by both patients and carers. The study confirmed that a decline in a patient's World Health Organization functional class, which indicates an increase in clinical severity of the disease, is associated with greater limitations. Results from the survey demonstrate the need for multidisciplinary PAH management and a comprehensive standard of care to assess and improve all aspects of well-being for both patients and carers. In addition, they underline the need for updated PAH guidelines that address these needs. @ERSpublications PAH has a profound impact on numerous aspects of patients' and carers' lives http://ow.ly/pWWYf This article has supplementary material available from err.ersjournals.comFull survey results, along with a call to action, are available at www.phaeurope.org/projects-activities/pah-patient-andcarer-survey

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“…It should be noted in Whitebird and colleagues' [ 36 ] study that the caregiver education and support intervention group also had increases in mental health, leading to an inference that a more supportive group format like MBCT may be even more effective for this population than MBSR. Lengacher and colleagues [ 39 ] found that in a study of advanced-stage cancer survivors and their caregivers that MBSR was helpful in increasing quality of life for caregivers, but that increase was not statistically signifi cant over time. Caregivers had lower levels of cortisol and interleukin-6 levels after the MBSR program, which indicated lower stress.…”

Section: Empirical Support Of Mbct For Caregivers Of Cancer Survivorsmentioning

confidence: 97%

Mindfulness-Based Cognitive Therapy and Caregivers of Cancer Survivors

Wood

Gonzalez

Barden

2016

Mindfulness-Based Cognitive Therapy

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A Pilot Study Evaluating the Effect of Mindfulness-Based Stress Reduction on Psychological Status, Physical Status, Salivary Cortisol, and Interleukin-6 Among Advanced-Stage Cancer Patients and Their Caregivers

Abstract: MBSR-C may be a beneficial intervention for reducing stress, anxiety, cortisol levels, and symptoms in advanced-stage cancer patients and may also benefit caregivers.

Cited by 127 publications

References 59 publications

A Mindfulness-Based Program Improves Health in Caregivers of People with Autism Spectrum Disorder: a Pilot Study

A Mindfulness-Based Program Improves Health in Caregivers of People with Autism Spectrum Disorder: a Pilot Study

Understanding the impact of pulmonary arterial hypertension on patients' and carers' lives

Mindfulness-Based Cognitive Therapy and Caregivers of Cancer Survivors

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