Abstract:This study aimed to retrospectively investigate the effect of bone graft after extraction of wisdom teeth impacting with the distal aspect of the second molar, on soft tissue wound healing, bone loss, and periodontal parameters. Sixteen patients treated an for impacted mandibular wisdom tooth at least one year ago were re-called (18 teeth). Dental panoramic tomography and periodontal parameters were assessed. A graft material was used to fill the post-extractive sockets in the test group (GUIDOR easy-graft CRY… Show more
“…There is, however, no consensus as to the optimum technique or choice of a biomaterial when carrying out SA. More recently, PRF has been used to enhance tissue regeneration in conjunction with SA [ 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 ].…”
Section: Indications For Socket Augmentationmentioning
After tooth extraction, the alveolar ridge undergoes a physiological process of remodelling and disuse atrophy. Socket augmentation (SA) has been shown to preserve alveolar bone volume in order to facilitate implant placement and reduce the need for staged grafting at a later date. Although autogenic grafting has been shown to be the gold standard in bone regeneration, it has significant disadvantages. To prevent post-extraction volumetric alterations and alveolar bone resorption occurring, alternative grafting materials, including xenografts, alloplasts, and allografts, have been used successfully in fresh extraction sites. However, these materials act mostly as bio-scaffolds and require a slower integration period of 6–8 months prior to implant placement. Recently, the use of autologous platelet-rich fibrin (PRF) has been advocated alongside socket augmentation as a method of bio-enhancement of healing of soft and hard tissues. PRF contains platelet-derived growth factors, hormones, and bioactive components such as cytokines that have been shown to promote angiogenesis and tissue regeneration during wound healing. The aim of this article is to review the evidence base for the SA technique Clinical benefits of SA will be discussed with a reference to two cases. Therefore, this narrative review will discuss the post-extraction bone changes, the importance of SA, and the bio-enhancement role of PRF in the management of extraction site defects when the alternative technique of immediate implant placement is not possible or contraindicated.
“…There is, however, no consensus as to the optimum technique or choice of a biomaterial when carrying out SA. More recently, PRF has been used to enhance tissue regeneration in conjunction with SA [ 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 ].…”
Section: Indications For Socket Augmentationmentioning
After tooth extraction, the alveolar ridge undergoes a physiological process of remodelling and disuse atrophy. Socket augmentation (SA) has been shown to preserve alveolar bone volume in order to facilitate implant placement and reduce the need for staged grafting at a later date. Although autogenic grafting has been shown to be the gold standard in bone regeneration, it has significant disadvantages. To prevent post-extraction volumetric alterations and alveolar bone resorption occurring, alternative grafting materials, including xenografts, alloplasts, and allografts, have been used successfully in fresh extraction sites. However, these materials act mostly as bio-scaffolds and require a slower integration period of 6–8 months prior to implant placement. Recently, the use of autologous platelet-rich fibrin (PRF) has been advocated alongside socket augmentation as a method of bio-enhancement of healing of soft and hard tissues. PRF contains platelet-derived growth factors, hormones, and bioactive components such as cytokines that have been shown to promote angiogenesis and tissue regeneration during wound healing. The aim of this article is to review the evidence base for the SA technique Clinical benefits of SA will be discussed with a reference to two cases. Therefore, this narrative review will discuss the post-extraction bone changes, the importance of SA, and the bio-enhancement role of PRF in the management of extraction site defects when the alternative technique of immediate implant placement is not possible or contraindicated.
“…32 Clinicians can make a chairside bone graft with a particle size ranging from 300 to 1200 mm that is disinfected and can be used in 8 minutes using a commercial tooth grinding device (i.e., tooth transformer or dentin grinder). 33 The resulting particle volume is roughly two to three times the tooth's original volume. (i.e., a tooth weighing 0.25 g produces at least 1 cm 3 of particulate).…”
To treat osseous defects, a range of bone grafts and their replacements have been accessible, but appropriate reconstruction by any bony defect persists as a therapeutic hurdle. Based on peer-reviewed literature, the current narrative review analyzes significant outcomes in patients treated with bone grafts and bone graft substitutes for surgical therapy of osseous defects. Despite autograft, xenograft, and alloplastic bone graft substitutes being employed in several periodontic procedures, they all have their restrictions. Autogenous tooth bone graft is functional in clinics due to different available forms, which can be availed for other clinical challenges. Moreover, genetic uniformity fosters efficient bone regeneration by allowing osteoinduction and osteoconduction and reducing foreign body reactions.
“…[ 8 ] In clinical practice, medical collagen sponge functions as auxiliary material to promote wound healing. [ 9 ] It remains unclear whether medical collagen sponge is effective in treating infants with burn wounds. In the current investigation, we compared and analyzed the clinical efficacy of rhGM-CSF gel, medical collagen sponge and rhGM-CSF gel in combination with medical collagen sponge on deep second-degree burn wounds of head, face or neck in infants.…”
Background:
This study aimed to observe clinical efficacy of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) gel, medical collagen sponge and rhGM-CSF gel in combination with medical collagen sponge on deep second-degree burns of head, face or neck in infants.
Methods:
A total of 108 infants with deep second-degree burns on head, face or neck were randomly divided into rhGM-CSF group, medical collagen sponge group, and rhGM-CSF + medical collagen sponge group. The scab dissolving time, healing time, bacterial positive rate and Vancouver scar scale were evaluated and analyzed.
Results:
The data analysis showed that scab dissolving time and healing time were shorter in rhGM-CSF + medical collagen sponge group than that in rhGM-CSF group and medical collagen sponge group, and the difference was statistically significant (P < .05). Bacterial positive rate was lower in rhGM-CSF + medical collagen sponge group than that in rhGM-CSF group and medical collagen sponge group (P < .05). After 3 months, score of Vancouver scar scale (scar thickness, pliability, pigmentation and vascularity) was less in rhGM-CSF + medical collagen sponge group than that in rhGM-CSF group and medical collagen sponge group (P < .05).
Conclusion:
rhGM-CSF gel in combination with medical collagen sponge is significantly effective in treating deep second-degree burns of head, face or neck in infants. This combination is beneficial for infection control, acceleration of scab dissolving and wound healing, and reduction of scar hyperplasia and pigmentation, which is worthy of clinical application and promotion.
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