A pilot, randomized controlled trial to examine the health outcomes of raisin consumption in patients with diabetes

Kanellos, P.; Kaliora, Andriana C.; Tentolouris, Nikolaοs; Argiana, Vasiliki; Περρέα, Δέσποινα; Kalogeropoulos, Nick; Kountouri, Aggeliki M.; Karathanos, Vaios Τ.

doi:10.1016/j.nut.2013.07.020

Cited by 57 publications

(74 citation statements)

References 29 publications

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“…Mechanisms related to the potential benefits of raisin intake for weight management have not been critically explored. A few intervention studies did not find any effect of raisins on body weight in people with type 2 diabetes [9] or in overweight or obese subjects with elevated glucose [10]. Small clinical studies suggest that raisins may increase satiety and decrease appetite [14,15].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Human intervention studies have reported mixed results on the effects of raisins on BP [9–11]. Raisin intake did not affect the lipid profile of fasting glucose or insulin in clinical studies [9–11]. However, raisins have consistently been demonstrated to lower postprandial glycemia and/or insulinemia in acute human feeding studies with healthy and diabetic subjects [10–13].…”

Section: Discussionmentioning

confidence: 99%

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Association of raisin consumption with nutrient intake, diet quality, and health risk factors in US adults: National Health and Nutrition Examination Survey 2001–2012

Fulgoni¹,

Painter²,

Carughi³

2017

Food & Nutrition Research

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Raisins are one of the most commonly consumed dried fruits. Because of their unique nutrient profile, raisins may have some distinctive health benefits. The purpose of this study was to examine the cross-sectional association between raisin consumption and nutrient intake, dietary quality, body weight, and metabolic syndrome risk factors in adults. Data from the National Health and Nutrition Examination Survey (NHANES), 2001–2012 (n = 29,684) were used. Raisin consumers (n = 458, 60% female) were defined as those having any amount of raisins during the first 24 h dietary recall. Diet quality was calculated using the Healthy Eating Index-2010 (HEI-2010). Covariate (demographic and lifestyle)-adjusted regression analyses were conducted using appropriate sample weights and significance was set at p < 0.01. Raisin consumers had higher intakes of energy (9%); higher intakes of ‘nutrients of public health concern/shortfall nutrients’, such as dietary fiber (34%), potassium (16%), magnesium (22%), vitamin C (24%), and vitamin E (22%); and lower intakes of ‘nutrients to limit’, such as added sugar (−17%), saturated fat (−15%), and sodium (−10%), than non-consumers. No associations were observed for intakes of calcium, iron, vitamin A, vitamin D, and folate. Consumers had higher intakes of total fruit (72%), whole fruit (111%), vegetables (22%), and whole grains (109%), and had a higher diet quality, as indicated by 25% higher total HEI-2010 scores than non-consumers. Compared to non-consumers, raisin consumers had a lower body weight (−4.2%), body mass index (−5.2%), and waist circumference (−3.8%), were 39% less likely to be overweight or obese, and had a 54% reduced risk of metabolic syndrome. In conclusion, raisin consumption was associated with better nutrient intake, diet quality, and weight parameters, and with lower risk of being obese and having metabolic syndrome in US adults.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Association of raisin consumption with nutrient intake, diet quality, and health risk factors in US adults: National Health and Nutrition Examination Survey 2001–2012

Fulgoni¹,

Painter²,

Carughi³

2017

Food & Nutrition Research

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“…Raisins also contain various phytochemicals including flavonoids (catechins, quercetin, kaempferol, and rutin), hydrocinnamic acids (coutaric and cafterics), epicatechins, phytoestrogens (genestein and daidzein), and resveratrol [Karadeniz, Durst, & Wrolstad, 2000; Williamson & Carughi, 2010], but the physiological consequences of consumption of these compounds remain to be elucidated. However, intervention studies examining nutritional and health effect of raisin consumption have been mostly limited to adults [Williamson & Carughi, 2010; Anderson & Waters, 2013; Kanellos et al., 2014; Anderson, Weiter, Christian, Ritchey, & Bays, 2014; Bays, Weiter, & Anderson, 2015; Kanellos et al., 2013; Esfahani, Lam, & Kendall, 2014; ]. Satiating effects of raisins have been reported in a couple of studies with children [Patel, Luhovyy et al., 2013; Patel, Luhovyy, Mollard, Painter, & Anderson, 2013].…”

Section: Introductionmentioning

confidence: 99%

Association of raisin and raisin‐containing food consumption with nutrient intake and diet quality in US children: NHANES 2001‐2012

Fulgoni

Painter²,

Carughi³

2018

Food Science & Nutrition

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BackgroundRaisins are a commonly consumed dried fruit and given their nutrient profile may offer nutritional and health benefits.ObjectiveTo examine the association between consumption of raisins and raisin‐containing foods with nutrient intake and dietary quality in children.MethodsNational Health and Nutrition Examination Survey (NHANES) data for 2001–2012 in those 2–18 years of age (n = 20,175) were used. Consumers of raisins (n = 154, 51.6% female) and raisin‐containing foods (n = 1,993, 52.5% female) were defined as reporting any consumption of raisins and raisin‐containing foods, respectively, during the first 24‐hr diet recall. Diet quality was assessed using the Healthy Eating Index (HEI)‐2010. Regression analyses were conducted comparing consumers and nonconsumers using appropriate sample weights and adjusted for demographic and lifestyle covariates with significance set at p < 0.01.ResultsRegarding “nutrients of public health concern/shortfall nutrients” and “nutrients to limit,” raisin consumers had higher intakes of dietary fiber (23%), potassium (16%), magnesium (12%) with lower intakes of added sugars (−19%) than nonconsumers. Similarly, consumers of raisin‐containing foods also had higher intakes of dietary fiber (15%), potassium (5%), magnesium (11%), iron (6%), vitamin A (10%), and vitamin E (13%) and lower intake of sodium (−5%). Consumers of raisin and raisin‐containing foods had higher intakes of fruits (60%, 16%, respectively), whole fruits (119%, 23%, respectively) and whole grains (44%, 93%, respectively) and had a better diet quality as per higher total HEI 2010 scores (22%, 8%, respectively) than nonconsumers.ConclusionIn conclusion, consumption of raisins or raisin‐containing foods was associated with better nutrient intake and diet quality in American children.

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“…Kanellos et al 55 analyzed the effect of raisin consumption on fasting glucose, glycated hemoglobin (HbA1 c ), antioxidant status, and blood pressure in individuals with T2DM. Subjects were instructed to consume two fruit servings of raisins (36 g/d) in place of a snack with similar energy density.…”

mentioning

confidence: 99%

A Comprehensive review of raisins and raisin components and their relationship to human health

Schuster¹,

Wang

Hawkins

et al. 2017

J Nutr Health

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A pilot, randomized controlled trial to examine the health outcomes of raisin consumption in patients with diabetes

Cited by 57 publications

References 29 publications

Association of raisin consumption with nutrient intake, diet quality, and health risk factors in US adults: National Health and Nutrition Examination Survey 2001–2012

Association of raisin consumption with nutrient intake, diet quality, and health risk factors in US adults: National Health and Nutrition Examination Survey 2001–2012

Association of raisin and raisin‐containing food consumption with nutrient intake and diet quality in US children: NHANES 2001‐2012

A Comprehensive review of raisins and raisin components and their relationship to human health

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