“… 1 Cytotoxic lesions of the corpus callosum are caused by a long list of different factors that include antiepileptic drugs, withdrawal of antiseizure drugs, epilepsy, migraine with aura, trauma, viruses (Epstein-Barr virus, rotavirus, influenza, parainfluenza, measles, mumps, cytomegalovirus, varicella-zoster, human herpesvirus‐6, human herpesvirus‐7, adenovirus, human parvovirus B19, rubella, human immunodeficiency virus, and enterovirus), bacteria (Salmonella enteritidis, Staphylococcus aureus, Legionella pneumophila, Escherichia coli, Klebsiella pneumoniae, Mycoplasma pneumoniae, Streptococcus pneumoniae, Campylobacter jejuni, and Enterococcus faecalis), malaria parasite, dengue fever, Kawasaki disease, renal failure, hemolytic uremic syndrome, autoimmune diseases, radiation therapy, metabolic diseases, mumps vaccine, malignancy, subarachnoid hemorrhage, high-altitude cerebral edema, and several pharmacological and toxic substances. 1 - 2 , 7 It is important to notice that CLOCCs have been recently associated with COVID-19 and SARS-CoV-2 mRNA vaccine (BNT162b). 3 - 4 To our knowledge, this is the second case of CLOCCs after SARS-CoV-2 vaccination described in the literature.…”