A photoconverter gel‐assisted blue light therapy for the treatment of rosacea

Fluorescent light energy: Treating rosacea subtypes 1, 2, and 3

“…FLE is a relatively new technology with a broad utility, including treating inflammatory skin conditions . Previous clinical work has shown that FLE can successfully target inflammation, reduce redness, and the associated lesions in acne vulgaris, as well as targeting inflammation and erythema in PPR, where topical treatment with metronidazole and ivermectin was ineffective …”

“…We have previously reported a beneficial effect of the Kleresca® biophotonic platform in treating papulopustular rosacea (subtype 2), where FLE reduced the inflammatory reaction and enhanced the skin's texture. 12 This study sought to demonstrate the application of FLE beyond subtype 2 and investigated its applicability to all three subtypes of rosacea.…”

“…15 Previous clinical work has shown that FLE can successfully target inflammation, reduce redness, and the associated lesions in acne vulgaris, [13][14][15] as well as targeting inflammation and erythema in PPR, where topical treatment with metronidazole and ivermectin was ineffective. 12 Recent work has explored some of the cellular mechanisms of FLE. 15 It has been shown to enhance collagen production from human dermal fibroblasts, attenuate the inflammatory signature of a variety of cutaneous cells, and induce neovascularization in vitro.…”

“…6,10 Recently, a novel biophotonic platform -Kleresca® biophotonic platform (consisting of a multi-light emitting diode (LED) lamp and proprietary chromophore containing gel) utilizing fluorescent light energy (FLE) -has emerged as a new therapy for treating inflammatory skin conditions. [11][12][13][14][15] Beneficial effects of FLE, such as reducing inflammation and associated redness have been reported in acne vulgaris [13][14][15] and PPR. 12 Further, FLE also has skin healing and rejuvenating properties as a stand-alone treatment 16 or when used as a post interventional therapy.…”

“…[11][12][13][14][15] Beneficial effects of FLE, such as reducing inflammation and associated redness have been reported in acne vulgaris [13][14][15] and PPR. 12 Further, FLE also has skin healing and rejuvenating properties as a stand-alone treatment 16 or when used as a post interventional therapy. 17 This study sought to expand the original reports of the benefit of FLE in PPR to other 'subtypes' of rosacea.…”