2021
DOI: 10.1016/j.chaos.2021.110854
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A phenomenological estimate of the true scale of CoViD-19 from primary data

Abstract: Estimation of the prevalence of undocumented SARS-CoV-2 infections is critical for understanding the overall impact of CoViD-19, and for implementing effective public policy intervention strategies. We discuss a simple yet effective approach to estimate the true number of people infected by SARS-CoV-2, using raw epidemiological data reported by official health institutions in the largest EU countries and the USA.

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Cited by 7 publications
(6 citation statements)
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“…As regard with the epidemiological side, and following Palatella et al [54], Vanni et al [67], the reproduction number is a function of s t which is the share of susceptible population (not immunized individuals), R t 0 is the reproduction number at the beginning of the observed period, and B t is the transmission rate function which depends on variables which describe the interaction frequency of contacts and the rate of becoming infected after a contact. Furthermore it also depends on the infectious age of individuals in the contagion process.…”
Section: Model and Resultsmentioning
confidence: 99%
“…As regard with the epidemiological side, and following Palatella et al [54], Vanni et al [67], the reproduction number is a function of s t which is the share of susceptible population (not immunized individuals), R t 0 is the reproduction number at the beginning of the observed period, and B t is the transmission rate function which depends on variables which describe the interaction frequency of contacts and the rate of becoming infected after a contact. Furthermore it also depends on the infectious age of individuals in the contagion process.…”
Section: Model and Resultsmentioning
confidence: 99%
“…Other methodological statistical studies have tried to estimate the true number of COVID-19-infected people indirectly. Palatella et al [ 4 ] tried to estimate the number of cases based on PCR test alone and Noh and Danuser [ 68 ] based on government daily counts of confirmed cases. However, these estimates could underestimate the real proportion since the data are related to the specific population.…”
Section: Discussionmentioning
confidence: 99%
“…Such cases are mostly asymptomatic or paucisymptomatic, as their lack or scarcity of symptoms does not reach the attention of the healthcare system. Undocumented cases have been found to expose a higher proportion of the population due to the lack of quarantine measures [ 4 ] and to be hard to recognize, as asymptomatic or mildly symptomatic patients often do not seek medical attention due to a lack of symptoms [ 5 ]. While challenging, the prevalence estimation for asymptomatic and mildly symptomatic cases is very important given the highly contagious nature of the virus.…”
Section: Introductionmentioning
confidence: 99%
“…In this context, it's important to note that informational entropy serves as a crucial variable in determining the effective reproduction number of an epidemic. The reproduction number R t has been estimated via a renewal epidemic model as developed in [59,60]. The human mobility regularity pattern influences the epidemiological evolution as follows: Proposition 3.…”
Section: Economic Activity Mobility Patterns and Epidemiological Evol...mentioning
confidence: 99%