2008
DOI: 10.1200/jco.2008.26.15_suppl.9513
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A phase III randomized study comparing the effects of oxandrolone (Ox) and megestrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy

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Cited by 20 publications
(18 citation statements)
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“…We obviously did not include agents or treatments that were developed for their anticachectic potential later on, such as insulin treatment [67], oxandrolone [68], and olanzapine [69].…”
Section: Discussionmentioning
confidence: 99%
“…We obviously did not include agents or treatments that were developed for their anticachectic potential later on, such as insulin treatment [67], oxandrolone [68], and olanzapine [69].…”
Section: Discussionmentioning
confidence: 99%
“…This study showed that patients treated with oxandrolone experienced an increase in lean body mass, a reduction in fat mass, and fewer self-reported anorectic symptoms 31. The side effects of these agents include elevated transaminase levels (especially with nandrolone), decreased high-density lipoprotein levels, interactions with oral anticoagulants, oral hypoglycemics, and adrenal steroids, and hypogonadism (with decreased systemic testosterone levels).…”
Section: Treatment Of Cacsmentioning
confidence: 90%
“…Hence, randomized controlled trials are warranted. that patients treated with oxandrolone experienced an increase in LBM, a reduction in fat mass and reduced self-reported anorectic symptoms [9 ]. However, these preliminary results should be considered with caution.…”
Section: Ghrelin Mimetics With Orexigenic and Anabolic Activitymentioning
confidence: 67%
“…A new formulation of marine fatty acids with more than 50% of phospholipid-bound fatty acids EPA and docosahexaenoic acid was investigated [9 ]. Thirty-one cancer patients with weight loss received marine phospholipids (1.5 g/day) as soft gel capsules for 6 weeks.…”
Section: Marine Phospholipidsmentioning
confidence: 99%