Abstract:Background/Objective:
With the increasing interest in natural products a phase I open label study of OMN54 (Aneustat™) in
patients with advanced malignancies was initiated to determine toxicity, maximum tolerated dose (MTD), dose limiting toxicities (DLT), and
pharmacokinetics (PK). OMN54 is a multitargeted agent, combining three Chinese botanicals; Ganoderma lucidium, Salvia miltiorrhiza and
Scuteliaria barbata.
Methods:
Eligible patients (pts) were >18 years of age with advanced solid tumors, able to s… Show more
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