Abstract:TPS816 Background: HER2 overexpression is well established as a therapeutic target in breast cancer and can be seen in a variety of gastrointestinal malignancies, notably in gastroesophageal cancer where positivity ranges from 4.4% to 53.4%. The recent approval of HER2-targeted therapies to treat gastroesophageal adenocarcinomas has validated HER2 as an actionable target in these diseases. Recent data also support the emerging role of HER2 directed therapy in colorectal cancer, among other solid tumors. Altho… Show more
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