A peptide fraction from hardened common beans (Phaseolus vulgaris) induces endothelium-dependent antihypertensive and renal effects in rats

Ribeiro, Juliana Vila Verde; Graziani, Daniel; Carvalho, Jhulle Horrane Moreira; Mendonça, Michelle Mendanha; Naves, Lara Marques; Oliveira, Helton Freires; Campos, Hericles Mesquita; Fíoravantí, Maria Clorínda Soares; Pacheco, Lílian Fernanda; Ferreira, Patrícia; Pedrino, Gustavo Rodrigues; Ghedini, Paulo César; Fernandes, Kátia Flávia; Batista, Karla de Aleluia; Xavier, Carlos Henrique

doi:10.1016/j.crfs.2022.100410

Cited by 3 publications

(1 citation statement)

References 44 publications

(57 reference statements)

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“…Ribeiro et al ( 138 ) described a dose-dependent antihypertensive effect in spontaneously hypertensive Wistar rats treated with common bean protein extract (<3 kDa). Which was related to the presence of short peptide sequences related to cardioprotective activities (i.e., VSE, EV, AVT, DF, ELL, SF, AF, VLL, PLL, and GF).…”

Section: Micronutrientsmentioning

confidence: 99%

Nutritional, bioactive components and health properties of the milpa triad system seeds (corn, common bean and pumpkin)

et al. 2023

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The milpa system is a biocultural polyculture technique. Heritage of Mesoamerican civilizations that offers a wide variety of plants for food purposes. Corn, common beans, and pumpkins are the main crops in this agroecosystem, which are important for people’s nutritional and food security. Moreover, milpa system seeds have great potential for preventing and ameliorating noncommunicable diseases, such as obesity, dyslipidemia, type 2 diabetes, among others. This work reviews and analyzes the nutritional and health benefits of milpa system seeds assessed by recent preclinical and clinical trials. Milpa seeds protein quality, vitamins and minerals, and phytochemical composition are also reviewed. Evidence suggests that regular consumption of milpa seeds combination could exert complementing effect to control nutritional deficiencies. Moreover, the combination of phytochemicals and nutritional components of the milpa seed could potentialize their individual health benefits. Milpa system seeds could be considered functional foods to fight nutritional deficiencies and prevent and control noncommunicable diseases.

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Section: Micronutrientsmentioning

confidence: 99%

Nutritional, bioactive components and health properties of the milpa triad system seeds (corn, common bean and pumpkin)

et al. 2023

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Extraction of capsaicin from Capsicum chinense (cv Bhut Jolokia) using supercritical fluid technology and degradation kinetics

et al. 2023

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Capsaicin (CC), the dominant pungent compound in hot chilies, is widely used as a flavouring agent, preservative, active compound in packaging film and functional foods. Capsicum chinense cv Bhut Jolokia is one of the richest sources of CC, yet scarcely studied. The present investigation aimed to optimize a clean and green method for extracting CC through supercritical fluid extraction (SFE) method. Low-grade, culled, and discarded fruits were used for the extraction, and process was optimized through central composite design of RSM. The optimized extraction condition, 68.31 ℃/347.98 bars/102.50 min, resulted in maximum CC content (367.14 ± 1.12 mg/g) and oleoresin yield (7.23 ± 2.15 %) in a shorter extraction time (< 2 h). Accelerated thermal stability study suggested first-order degradation kinetics of CC at temperatures from 80 to 140 ℃. The activation energy (kJ/mol) of the reaction was 71.86, while Q10 for 80 to 100 ℃, 100 to 120, and 120 to 140 were 0.0548, 0.0574, and 0.1456, respectively. Valorisation of Bhut Jolokia for targeting an oleoresin with maximum CC opens a new window for its commercial exploitation in food industry. Furthermore, the study opens avenues for exploration of SFE-based extraction as clean, and sustainable method with reduced carbon footing.

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Legume-derived bioactive peptides: role in cardiovascular disease prevention and control

Fonseca Hernandez,

Mojica,

Gonzalez de Mejia

2024

Current Opinion in Food Science

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A peptide fraction from hardened common beans (Phaseolus vulgaris) induces endothelium-dependent antihypertensive and renal effects in rats

Cited by 3 publications

References 44 publications

Nutritional, bioactive components and health properties of the milpa triad system seeds (corn, common bean and pumpkin)

Nutritional, bioactive components and health properties of the milpa triad system seeds (corn, common bean and pumpkin)

Extraction of capsaicin from Capsicum chinense (cv Bhut Jolokia) using supercritical fluid technology and degradation kinetics

Legume-derived bioactive peptides: role in cardiovascular disease prevention and control

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