A Peep in to Novel Therapies in Diabetic Foot Ulcer

Abstract

Diabetic Foot Ulcer represent a complex entity resulting from several contributing pathways including neuropathy, vascular disease, and metabolic derangement, which may occur alone or in concert with each other. DFU affects patients physically, mentally and economically. Offloading, debridement, infectious controlling and revascularization remains as the mainstay in treatment of diabetic foot. Antibiotic resistance are also observed frequently in these patients. These current standard of treatment is still not showing much recovery in patients. In this era novel approaches to the treatment of DFU gain more interest. This review aims to summarize the novel approaches that are in practice for the diabetic foot ulcer treatment along with clinical evidences from the randomized control trials. Still many procedures lack much evidence and their efficacy and safety need to be determined.