“…Several of these encounters, including those of the index patient, transpired during the height of the COVID-19 pandemic, when hospitals were grappling with overwhelming patient volumes in emergency departments and intensive care units, as well as unprecedented staffing and blood shortages. 14 The ramifications of this behavior are not confined to wasted resources. Rather, there is risk of deleterious effect from the interventions (e.g., blood transfusion and tPA) that are commonly utilized for complications of “SCD”.…”