A pair of SARS-CoV-2 nucleocapsid protein monoclonal antibodies shows high specificity and sensitivity for diagnosis

Zhu, A Ying; Li, Sa-Sa; Yu, Shu-Pei; Zhang, Zhaoyong; Li, Huan; Li, Jing‐Feng; Gao, Shanshan; Chen, Heng; Zhao, Jincun; Shi, Run; Lu, Mingjian; Li, Chaoyang

doi:10.1016/j.virs.2022.10.003

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Remdesivir-loaded Nanocomposites Inhibit Sars-cov-2 Infectio...1

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2024

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“…39,46 To visualize the inhibition of SARS-CoV-2, an immunouorescence assay was performed in accordance with protocols outlined in previous studies to detect SARS-CoV-2 nucleocapsid proteins. 43,47 Nucleocapsid antibody staining on SARS-CoV-2 infected Vero E6 cells enabled visualizing the viral load in various treatment groups. Clearly, both RDV NPs and RDV NCs have shown more than 80% viral inhibition without inducing cytotoxicity as seen by nuclei staining (Fig.…”

Section: Remdesivir-loaded Nanocomposites Inhibit Sars-cov-2 Infectio...mentioning

confidence: 99%