A One‐Step Synthesis of γ‐Keto Carboxylic Acids

Abstract

If the alkane is volatile, c.g. when R' = CzH5, this reaction can be used for quantitative estimation of the organolead hydride. Benzyl chloride, o3-bromoacetophenone, ally1 bromide, bromobenzene, and iodobenzene are dehalogenated in this manner at 0 OC; triethyltin chloride gives rise to the hydride, 1,2-dibromoethane to ethylene, and carbon tetrachloride selectively to chloroform or dichloromethane. Benzaldehyde and nitrobenzene are also reduced at O°C. Received: J u n e 8th. 1965 [Z 14/839 1EJ German version: Angew. Chem. 77, 808 (1965) Publication deferred until now at the authors' request