A one-pot synthesis of 2H-pyrido[1,2-a][1,3,5]triazine-2-selenones from acyl isoselenocyanates and pyridin-2-amine

Synthesis of 4-aryl-1,3,4a-Triazaphenanthrene-2-Selones via Three-Component Condensation of Quinolin-2-Amine, Potassium Selenocyanate and an Acyl Chloride

“…A recent report 17 described the synthesis of a series of aryl triazanaphthalene-selones by the reaction at room temperature in acetone solvent between 2-aminopyridine, an acyl chloride and potassium selenocyanate (KSeCN). We thought that a synthesis of some benzo analogues of the 4-aryl-1,3,4atriazaphenanthrene-2-selones (4) might be simply achieved by a similar reaction in which 2-aminopyridine was replaced by quinolin-2-amine (1) (Scheme 1).…”

“…15 Recently, a few syntheses of heterocycles from acyl isoselenocyanates have been reported. [16][17][18][19][20] Herein, we describe a synthesis of a series of new 4-aryl-1,3,4atriazaphenanthrene-2-selones using a reported method. 17…”

Synthesis of 5-Aryl-1,3-Dimethyl-7-Selenoxopyrimidino[4,5-d]Pyrimidine-2,4(1H,3H)-Dione

“…11 Recently, a few syntheses of heterocycles from acyl isoselenocyanates have been reported. [12][13][14][15] Also, in 2011, a synthesis of functionalised pyrimido [4,5-d] pyrimidines from acyl isothiocyanates was reported. 16 Herein, we describe a synthesis of some seleno analogues, namely 5-aryl-1,3-dimethyl-7-selenoxopyrimidino [4,5-d]pyrimidine-2,4(1H,3H)-dione 4, by the reaction of acyl isoselenocyanates, generated from acyl chlorides and potassium selenocyanate, with 6-amino-N,N′-dimethyluracil in acetone using a reported method.…”

“…16 Herein, we describe a synthesis of some seleno analogues, namely 5-aryl-1,3-dimethyl-7-selenoxopyrimidino [4,5-d]pyrimidine-2,4(1H,3H)-dione 4, by the reaction of acyl isoselenocyanates, generated from acyl chlorides and potassium selenocyanate, with 6-amino-N,N′-dimethyluracil in acetone using a reported method. 12…”

Synthesis ofN-(3-Methyl-4-Phenyl-3H-Selenazol-2-Ylidene)Benzamide Derivatives

“…12 Recently, a synthesis of 2H-pyrido[1,2-a] [1,3,5]triazine-2-selenones from acyl isoselenocyanates and pyridin-2-amine at room temperature was reported. 13 Also, the synthesis of 1,2,4-triazole-3-selenones from acyl isoselenocyanates, and benzohydrazide under solvent-free conditions at ambient temperature has been reported. 14 [1,3]Oxazine derivatives have been generated from acyl isoselenocyanates and 4-hydroxycoumarin in the presence of N-methylimidazole under solvent-free conditions at ambient temperature.…”