A one-pot approach for conversion of fructose to 2,5-diformylfuran by combination of Fe3O4-SBA-SO3H and K-OMS-2

One-flow syntheses of diverse heterocyclic furan chemicals directly from fructose via tandem transformation platform

“…In comparison, the best yield reported in the literature by a one-pot reaction with the stepwise addition of the two heterogeneous catalysts was 80% for 8 h at 110°C using a SBA-SO 3 H and K-OMS-2 serial catalyst system, which required the separation of the catalyst from the product solution. 8 However, the catalyst addition and separation steps were not needed in the integrated microfluidic process.…”

“…4 The synthesis of furan derivatives from carbohydrates typically involves multiple reaction steps, such as dehydration for HMF production, followed by further transformation in the presence of heterogeneous catalysts. 4,8 The synthesis of furan derivatives from HMF in a single step is well documented. However, the direct synthesis of the derivatives from carbohydrates is rarely reported and remains challenging because it requires a two-step process involving the isolation and purification of HMF as an intermediate and separation of the catalyst from the main stream, which is a time-, cost-and labor-consuming process.…”

“…6 A onepot catalytic process has been developed to remove the intermediate purification step in the multi-step syntheses. 6,8,9 However, the one-pot reaction generally requires a long reaction time extending to several tens of hours that often causes thermal degradation of the highly reactive furan ring molecules. 6,8 A set of catalysts in one pot could result in negative interference between catalysts, resulting in low efficiency of productivity.…”

“…6,8,9 However, the one-pot reaction generally requires a long reaction time extending to several tens of hours that often causes thermal degradation of the highly reactive furan ring molecules. 6,8 A set of catalysts in one pot could result in negative interference between catalysts, resulting in low efficiency of productivity. 10 Although the multi-functional catalysts allow several reaction steps to be completed in one reactor and avoid a costly intermediate separation process, 11 the recycling of the catalyst still remains an active topic in the downstream chemical processing technology.…”

Advances in selective catalytic transformation of ployols to value-added chemicals

“…It was found that NaBr inhibited the oxidation of HMF, and NaVO3·2H2O has a negative impact in the dehydration of glucose. Very recently, Fu and coworkers [108] demonstrated the direct synthesis of DFF from fructose via acid-catalyzed dehydration. Successive aerobic oxidation in the one-pot reaction was successfully catalyzed by a combination of Fe3O4-SBA-SO3H and K-OMS-2.…”