A One Health approach to prevention, treatment, and control of campylobacteriosis

Schiaffino, Francesca; Platts-Mills, James A; Kosek, Margaret

doi:10.1097/qco.0000000000000570

Cited by 15 publications

(11 citation statements)

References 113 publications

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“…Quinolone-resistant Campylobacter has been described worldwide at alarming rates. As a consequence, macrolides are presently recommended as the first-line therapy of human campylobacteriosis [41,42]. Several studies have reported high rates of quinolone resistance among Campylobacter isolated from retail food samples [5,43,44].…”

Section: Discussionmentioning

confidence: 99%

Occurrence and Multidrug Resistance of Campylobacter in Chicken Meat from Different Production Systems

Santos-Ferreira

Ferreira

Teixeira

2022

Foods

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Campylobacter is the leading bacterial cause of diarrheal disease worldwide and poultry remains the primary vehicle of its transmission to humans. Due to the rapid increase in antibiotic resistance among Campylobacter strains, the World Health Organization (WHO) added Campylobacter fluoroquinolone resistance to the WHO list of antibiotic-resistant “priority pathogens”. This study aimed to investigate the occurrence and antibiotic resistance of Campylobacter spp. in meat samples from chickens reared in different production systems: (a) conventional, (b) free-range and (c) backyard farming. Campylobacter spp. was detected in all samples from conventionally reared and free-range broilers and in 72.7% of backyard chicken samples. Levels of contamination were on average 2.7 × 103 colony forming units (CFU)/g, 4.4 × 102 CFU/g and 4.2 × 104 CFU/g in conventionally reared, free-range and backyard chickens, respectively. Campylobacter jejuni and Campylobacter coli were the only species isolated. Distribution of these species does not seem to be affected by the production system. The overall prevalence of Campylobacter isolates exhibiting resistance to at least one antimicrobial was 98.4%. All the C. coli isolates showed resistance to ciprofloxacin and to nalidixic acid, and 79.5 and 97.4% to ampicillin and tetracycline, respectively. In total, 96.2% of C. jejuni isolates displayed a resistant phenotype to ciprofloxacin and to nalidixic acid, and 92.3% to ampicillin and tetracycline. Of the 130 Campylobacter isolates tested, 97.7% were classified as multidrug resistant (MDR).

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Section: Discussionmentioning

confidence: 99%

Occurrence and Multidrug Resistance of Campylobacter in Chicken Meat from Different Production Systems

Santos-Ferreira

Ferreira

Teixeira

2022

Foods

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“…The antibiotics commonly used to treat Campylobacter infection include macrolides, fluoroquinolones, aminoglycosides, tetracyclines, and beta-lactams [8][9][10]. Less than 1% of C. jejuni and 10% of C. coli are resistant to macrolides, which are the first-line treatment [11].…”

Section: Discussionmentioning

confidence: 99%

“…Less than 1% of C. jejuni and 10% of C. coli are resistant to macrolides, which are the first-line treatment [11]. Fluoroquinolones can also be a treatment option; however, resistance to these is increasing, which limits their effectiveness (almost 50% of C. jejuni and 60% of C. coli, with studies reporting up to 90% resistance in humans) [9,11]. In cases of strains resistant to quinolones and macrolides, or disease progression, amoxicillin with clavulanic acid or carbapenems should be used, depending on the severity of the case [9,11].…”

Section: Discussionmentioning

confidence: 99%

“…Fluoroquinolones can also be a treatment option; however, resistance to these is increasing, which limits their effectiveness (almost 50% of C. jejuni and 60% of C. coli, with studies reporting up to 90% resistance in humans) [9,11]. In cases of strains resistant to quinolones and macrolides, or disease progression, amoxicillin with clavulanic acid or carbapenems should be used, depending on the severity of the case [9,11]. Campylobacter species are inherently resistant to trimethoprim and some beta-lactams (penicillin and cephalosporins); therefore, these should be avoided [12].…”

Section: Discussionmentioning

confidence: 99%

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Renal Abscess and Recurrent Bacteremia Caused by Campylobacter Infection in an Adult With Common Variable Immunodeficiency

Cameira¹,

Araújo²,

Afonso³

et al. 2022

Cureus

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Campylobacter bacteremia and extraintestinal manifestations are extremely rare, occurring more frequently in immunocompromised patients. We report a rare clinical case of a 46-year-old female with common variable immunodeficiency (CVID) presenting with a previously undescribed extraintestinal complicationrenal abscess -and recurrent bacteremia caused by Campylobacter, which was a therapeutic challenge and required the use of secondary prophylactic antibiotic treatment to prevent recurrence.

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“…Bacteria Campylobacter spp. colonize the digestive tract of chickens during their first two weeks of life, and without causing any symptoms are released into the environment in large quantities with feces until slaughter (Schiaffino et al, 2019). In European countries, campylobacteriosis is the most common cause of infectious gastroenteritis.…”

Section: Campylobacteriosis (Campylobacter Spp)mentioning

confidence: 99%

Intensive animal farming operations and outbreaks of zoonotic bacterial diseases in Ukraine

Tsarenko

Korniienko²

2021

Regul. Mech. Biosyst.

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In Ukraine zoonoses are a permanent threat to human health, some of them are bacterial diseases associated with farm animals. Complete avoidance of outbreaks of bacterial zoonoses is not possible but it is appropriate to study them to reduce the risks of transmission of zoonosis pathogens from industrial farms to the human population and the environment. The article highlights the results of a literature review on the potential role of industrial livestock farms in the spread of major bacterial zoonoses in Ukraine. About half of all of the country’s farmed animals are kept on farms using industrial technology; more than half of the establishments are classified as medium and large. The technology of keeping animals on such farms contributes to the development of diseases of obligate hosts caused by fecal bacteria. The systematic search and selection of literary sources, which are relevant to the topic of the study were carried out. The vast majority of analyzed publications are published in Ukrainian in local peer-reviewed scientific journals. An analysis of open-access official statistics from the state authorities of Ukraine was also conducted. The authors analyzed statistics and scientific papers published over the last 10–15 years discussing the outbreaks of food-borne zoonoses among humans and the studying their pathogens (Campylobacter spp., Salmonella spp., Escherichia coli (STEC strains), Listeria spp.) on industrial livestock farms. The main source of Campylobacter spp. and Salmonella spp. distribution are industrial poultry, including broilers and chickens, respectively. The STEC strains E. coli carriers are various types of farm animals, including cattle and pigs. The majority of infections documented in Ukraine are cases of salmonellosis in humans and animals. Despite reports of a significant prevalence of campylobacteriosis, colibacillosis and listeriosis in livestock farms, their association with outbreaks of food-borne zoonoses in humans remains poorly understood. The concept of an industrial livestock farm involves a permanent presence of a risk of outbreaks of bacterial zoonoses and their rapid spreading to the human population. This is due to concentrated maintenance of animals, standardized feeding, the priority of achieving the highest productivity of animals and economic indicators. Under such conditions, disturbance of hygienic norms and technologies significantly increases the risk of bacterial zoonoses on industrial farms. It is important to enforce the continuous control of the level of microbial pollution of farms, animal health, hygiene of milk production and processing, meat, eggs, etc. Farms have a negative impact on the ecological welfare of the surrounding territories. The problem of spread of antibiotic-resistant strains of bacterial zoonoses is a very serious one. Efforts for the formation of a national system of epidemiological supervision over bacterial zoonoses, comprising epidemiological, epizootological, ecological, microbiological, serological and molecular genetic monitoring, as well as the development on this basis of effective prophylactic and anti-epidemic measures are relevant and necessary.

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A One Health approach to prevention, treatment, and control of campylobacteriosis

Cited by 15 publications

References 113 publications

Occurrence and Multidrug Resistance of Campylobacter in Chicken Meat from Different Production Systems

Occurrence and Multidrug Resistance of Campylobacter in Chicken Meat from Different Production Systems

Renal Abscess and Recurrent Bacteremia Caused by Campylobacter Infection in an Adult With Common Variable Immunodeficiency

Intensive animal farming operations and outbreaks of zoonotic bacterial diseases in Ukraine

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