This work discusses simulations using the detached eddy simulation based (DES) turbulence model to investigate turbulent channel flows. Applicability of Strelets' (2001) version of the DES model was tested for a fully developed turbulent channel flow problem in a rectangular duct. The unsteady Navier-Stokes equations were solved numerically at Reynolds number, Re s , of 180, 590, and 2000, respectively, and compared to results obtained using direct numerical simulation (DNS) and previously published DES data. Effects of grid density and advection scheme were investigated. Overall, the model predicted the correct trends in the variation of turbulence quantities and compared reasonably well.