A novel Y-shaped photoiniferter used for the construction of polydimethylsiloxane surfaces with antibacterial and antifouling properties

Abstract

The simultaneous introduction of two new functionalities into the same polymeric substrate under mild reaction conditions is an interesting and important topic. Herein, dual-functional polydimethylsiloxane (PDMS) surfaces with antibacterial and...

Recent Developments in Multifunctional Antimicrobial Surfaces and Applications toward Advanced Nitric Oxide-Based Biomaterials

“…Accordingly, efforts to find substitutes with higher stability have been directed toward an exploration of mixed polymer brushes, zwitterionic polymers, side chains, and surface grafts. , Neutral hydrophilic PEG alternatives, such as polyglycerol and poly­(2-methyl-2-oxazoline), have demonstrated protein resistance comparable to that of PEG controls and improved oxidative stability on polydopamine-modified surfaces. ,− Bacterial species consist of negatively charged surfaces because of the presence of ionic carbohydrate, teichoic acid, and lipopolysaccharide structures. Therefore, antibacterial agents with positively charged surfaces composed of particles, polymers, and peptides have been developed and extensively investigated for their dual-functional antibacterial behavior against a vast span of bacteria, including multidrug-resistant strains. − …”

Introducing SuFEx click chemistry into aliphatic polycarbonates: a novel toolbox/platform for post-modification as biomaterials

“…It is generally believed that positively charged macromolecules can effectively the bacterial membrane structure and thus exhibit favorable bactericidal effects. 34,62 Therefore, it is a promising strategy to integrate pFMCs and imidazolium-type ionic liquids (ILs) with proven antimicrobial properties. After the SuFEx reaction between pFMCs and silyl ether-protected ionic liquid (TBDMS-IL) (Scheme S6a, ESI †), the successful synthesis of pFMC-IL polymers was verified by 1 H NMR and GPC analyses (Fig.…”

“…As a guanidine Lewis base, 1,5,7-triazabicyclo[4,4,0]dec-5ene (TBD) has recently attracted interest in terms of catalysis of a wide range of chemical reactions, including SuFEx click chemistry [32][33][34] and ROP. [35][36][37][38] With the versatility of TBD as an organocatalyst, it is inspiring to explore the design of an APC system where ROP and PPM via SuFEx can be achieved synchronously and simultaneously without constraining or antagonizing each other.…”

Chemoselective Reactions of Functionalized Sulfonyl Halides

“…Activation with other coupling agents (e. g., EDC or HBTU) can also be used, although being less common for this type of substrates. [27,[50][51][52][53][54] Specific methods for the chemoselective ester formation tolerating the SO 2 F group include reaction with diazomethane [55] and alkylation of silver salts. [56] Other related transformations tolerating the SO 2 F moiety included ester hydrolysis, [57] synthesis of urea derivatives from p-nitrophenyl carbamates, [58] and formation of sulfonamides from sulfonyl chlorides (which is a good illustration of large difference in the SO 2 Cl and SO 2 F group reactivity) (Scheme 3).…”