A Novel Tram Stent Method in the Treatment of Coronary Bifurcation Lesions – Finite Element Study

Arokiaraj, Mark Christopher; Santis, Gianluca De; Beule, Matthieu De; Palacios, Igor F.

doi:10.1371/journal.pone.0149838

Cited by 8 publications

(24 citation statements)

References 51 publications

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“…Taeksu and Jang 21 explored the interactions of several stent types and arteries with different curvatures (0, 0.2, and 0.4) and indicated the recovery of stenotic artery. Similar studies have also been conducted as reported in Conway et al, 22 Morlacchi et al, 23 Ragkousis et al, 24 Schiavone and Zhao, 25 Arokiaraj et al, 26 Wei et al 27…”

Section: Introductionsupporting

confidence: 81%

Investigation of mechanical behaviors and improved design of V-shaped braid stents

Liu

Luo

et al. 2022

Proc Inst Mech Eng H

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V-shaped braid stents (VBSs), as highly retrievable and flexible nitinol stents, are extensively applied in endovascular diseases. They also cause less damage to vessel wall compared to tube-cutting stents. However, poor performance of VBS or suboptimal operation can give rise to unwanted clinical situations such as thrombosis and intimal hyperplasia. Therefore, research on designing factors affecting the performance of these devices is of great significance. Furthermore, simulation of stenting process can help designers understand the interactions of stents and vessel wall to reduce time to market. Thus, finite element analysis (FEA) and bench test are performed taking into account both designing factors and stenting process of VBS, including development of parametric modeling tool, research on the relationships among structural parameters and radial force, exploration of the interactions of VBS and vessel wall and pulsating load effect. This research was performed using a commercial solver Abaqus/standard with a user material subroutine (UMAT/nitinol). Structural parameters of VBS, unit-cell height and wire diameter have significant impacts on radial force, unit-cell number has slight influence on radial force, and arc diameter has almost negligible impact on radial force. Without pulsatile load, maximum stress and strain always occur in arc position; however, in pulsatile load, maximum stress and strain are gradually transformed to strut position. The stress created near vessel wall and VBS interface is higher than interaction stress due to pulsating load. The obtained result provided valuable information on the structural design of stents as well as the effects of stent on vessel wall and that vessel wall on stent deformation. Graphical abstract [Formula: see text]

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Section: Introductionsupporting

confidence: 81%

Investigation of mechanical behaviors and improved design of V-shaped braid stents

Liu

Luo

et al. 2022

Proc Inst Mech Eng H

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“…As Mg is a potential material for the stent applications, in this section, we are going to focus mainly on the application of FEA in the stent industry. Many researchers used this powerful tool to predict the performance of stents made of different materials including polymeric stents, Nitinol stents, stainless steel stents, and BMG‐based stents to name a few. FEA is in practice to analyze Mg stents for their mechanical performance and corrosion behavior.…”

Section: Computational Modelsmentioning

confidence: 99%

The current trends of Mg alloys in biomedical applications—A review

2018

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Magnesium (Mg) has emerged as an ideal alternative to the permanent implant materials owing to its enhanced properties such as biodegradation, better mechanical strengths than polymeric biodegradable materials and biocompatibility. It has been under investigation as an implant material both in cardiovascular and orthopedic applications. The use of Mg as an implant material reduces the risk of long-term incompatible interaction of implant with tissues and eliminates the second surgical procedure to remove the implant, thus minimizes the complications. The hurdle in the extensive use of Mg implants is its fast degradation rate, which consequently reduces the mechanical strength to support the implant site. Alloy development, surface treatment, and design modification of implants are the routes that can lead to the improved corrosion resistance of Mg implants and extensive research is going on in all three directions. In this review, the recent trends in the alloying and surface treatment of Mg have been discussed in detail. Additionally, the recent progress in the use of computational models to analyze Mg bioimplants has been given special consideration.

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“…Geometric modelling of biological structures by using tools based on computer-aided design (CAD) is currently applied to disease diagnosis [10,11], design of medical devices [12,13], and geometric reconstruction for different purposes [14,15]. More specifically, in the field of ophthalmology, there are several studies that use CAD methods to develop the concept of a patient-specific model [16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

A Study for Parametric Morphogeometric Operators to Assist the Detection of Keratoconus

et al. 2017

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Abstract:The aim of this study is to describe a new keratoconus detection method based on the analysis of certain parametric morphogeometric operators extracted from a custom patient-specific three-dimensional (3D) model of the human cornea. A corneal geometric reconstruction is firstly performed using zonal functions and retrospective Scheimpflug tomography data from 107 eyes of 107 patients. The posterior corneal surface is later analysed using an optimised computational geometry technique and the morphology of healthy and keratoconic corneas is characterized by means of geometric variables. The performance of these variables as predictors of a new geometric marker is assessed through a receiver operating characteristic (ROC) curve analysis and their correlations are analysed through Pearson or Spearman coefficients. The posterior apex deviation variable shows the best keratoconus diagnosis capability. However, the strongest correlations in both healthy and pathological corneas are provided by the metrics directly related to the thickness as the sagittal plane area at the apex and the sagittal plane area at the minimum thickness point. A comparison of the screening of keratoconus provided by the Sirius topographer and the detection of corneal ectasia using the posterior apex deviation parameter is also performed, demonstrating the accuracy of this characterization as an effective marker of the diagnosis and ectatic disease progression.

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A Novel Tram Stent Method in the Treatment of Coronary Bifurcation Lesions – Finite Element Study

Cited by 8 publications

References 51 publications

Investigation of mechanical behaviors and improved design of V-shaped braid stents

Investigation of mechanical behaviors and improved design of V-shaped braid stents

The current trends of Mg alloys in biomedical applications—A review

A Study for Parametric Morphogeometric Operators to Assist the Detection of Keratoconus

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