A novel synthesis for new substituted imidazoles

Abstract

This paper is dedicated to Professor Habib Firouzabadi on the occasion of his honourable retirement and for his continous, past and future devotions and endeavours to the field of organic chemistry.MMH owes him a personal debt of deep gartitude for his encourgments and friendships.The addition of dimethyl acethylendicarboxylate (DMAD) to thiosemicarbazone and guanylhydrazone of aldehydes afforded compoundes which were characterized to be new substituted imidazoles. Their structures were determined by 'n NMR, IR, mass spectra and elemental analyses.

The Behavior of (cyclic‐alkylidene)hydrazinecarbothioamides in Cyclization with Dimethyl acetylenedicarboxylate

“…It has been reported that, thioxoimidazole derivatives were isolated from the reaction of arylthiosemicarbazones with dimethyl acetylenedicarboxylate (DMAD) . Also, Vijesh et al suggested that imidazolethione derivatives containing substituted pyrazole moiety were obtained upon treatment of substituted thiosemi‐carbazones containing pyrazole ring with DMAD .…”