Researchers in exploration and development (E&D) field need several professional software resources for data processing and analysis. Enterprises can achieve cloud-based usage and shared management of petroleum exploration and development software through the deployment of cloud platforms. With the increasing demand for remote and overseas collaborative research, the single-node cloud platform deployment mode no longer meets the needs of collaborative research. This paper proposes a construction scheme of cloud platform for petroleum software based on distributed architecture, which realizes the unified management of software research environment, software licenses, and data. The proposed architecture has been implemented in a division of CNPC, realizing the cloudification of more than 20 mainstream professional E&D software applications such as Petrel and LandMark. By establishing central sites in Beijing and branch sites in Dubai and Hangzhou, the researchers are provided with a cross-regional collaborative research environment on the cloud, thereby enhancing the research efficiency, improving the efficiency of cross-regional collaborative research, and facilitating the unified data management and the digital transformation of petroleum enterprises in the cloud environment.