Abstract:Background
Pain is the primary reason people seek medical care, with chronic pain affecting ~ 20% of people in the USA. However, many existing analgesics are ineffective in treating chronic pain, while others (e.g., opioids) have undesirable side effects. Here, we describe the screening of a small molecule library using a thermal place aversion assay in larval zebrafish to identify compounds that alter aversion to noxious thermal stimuli and could thus serve as potential analgesics.
… Show more
“…The original article [ 1 ] erroneously presented a duplicate of Additional File 2 and omitted Additional File 6 due to a technical error on the publisher’s side. The affected Additional Files have since been amended.…”
“…The original article [ 1 ] erroneously presented a duplicate of Additional File 2 and omitted Additional File 6 due to a technical error on the publisher’s side. The affected Additional Files have since been amended.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.