A novel small diameter nanotextile arterial graft is associated with surgical feasibility and safety and increased transmural endothelial ingrowth in pig

Joseph, John; Bruno, Vito Domenico; Sulaiman, Nadiah; Ward, Amanda J.; Johnson, Tom; Baby, Helna Mary; Varma, Praveen Kerala; Jose, Rajesh; Nair, Shantikumar V.; Menon, Deepthy; George, Sarah J.; Ascione, Raimondo

doi:10.1186/s12951-022-01268-1

Cited by 6 publications

(7 citation statements)

References 51 publications

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“… Occlusion, platelet adhesion. [ 178 ] PHEA-PLA / PCL Pig, artificial blood vessel graft. Physicochemical property.…”

Section: Biomaterials Applications In MI Therapymentioning

confidence: 99%

Application of biomedical materials in the diagnosis and treatment of myocardial infarction

Zhang,

Guo,

Bai

et al. 2023

J Nanobiotechnol

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Myocardial infarction (MI) is a cardiovascular emergency and the leading cause of death worldwide. Inflammatory and immune responses are initiated immediately after MI, leading to myocardial death, scarring, and ventricular remodeling. Current therapeutic approaches emphasize early restoration of ischemic myocardial reperfusion, but there is no effective treatment for the pathological changes of infarction. Biomedical materials development has brought new hope for MI diagnosis and treatment. Biomedical materials, such as cardiac patches, hydrogels, nano biomaterials, and artificial blood vessels, have played an irreplaceable role in MI diagnosis and treatment. They improve the accuracy and efficacy of MI diagnosis and offer further possibilities for reducing inflammation, immunomodulation, inhibiting fibrosis, and cardiac regeneration. This review focuses on the advances in biomedical materials applications in MI diagnosis and treatment. The current studies are outlined in terms of mechanisms of action and effects. It is addressed how biomedical materials application can lessen myocardial damage, encourage angiogenesis, and enhance heart function. Their clinical transformation value and application prospect are discussed.

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“… Occlusion, platelet adhesion. [ 178 ] PHEA-PLA / PCL Pig, artificial blood vessel graft. Physicochemical property.…”

Section: Biomaterials Applications In MI Therapymentioning

confidence: 99%

Application of biomedical materials in the diagnosis and treatment of myocardial infarction

Zhang,

Guo,

Bai

et al. 2023

J Nanobiotechnol

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“…Additionally, the mechanical and biological functions of TEVGs need to be improved for TEVGs to make their way to the clinical use ( Konig et al, 2010 ). One of the main causes of vascular graft failure is the lack of a confluent endothelium due to the thrombogenicity of the graft ( Joseph et al, 2022 ; Weekes et al, 2022 ). Acellular and decellularized TEVGs are commonly affected by thrombosis and thereby early failure ( Owens et al, 2015 ).…”

Section: Tissue-engineered Vascular Graftsmentioning

confidence: 99%

Clinical implications of inflammation in atheroma formation and novel therapies in cardiovascular diseases

Barungi

Hernández-Camarero²,

Moreno-Terribas³

et al. 2023

Front. Cell Dev. Biol.

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Cardiovascular diseases (CVD) are the leading causes of death and disability in the world. Among all CVD, the most common is coronary artery disease (CAD). CAD results from the complications promoted by atherosclerosis, which is characterized by the accumulation of atherosclerotic plaques that limit and block the blood flow of the arteries involved in heart oxygenation. Atherosclerotic disease is usually treated by stents implantation and angioplasty, but these surgical interventions also favour thrombosis and restenosis which often lead to device failure. Hence, efficient and long-lasting therapeutic options that are easily accessible to patients are in high demand. Advanced technologies including nanotechnology or vascular tissue engineering may provide promising solutions for CVD. Moreover, advances in the understanding of the biological processes underlying atherosclerosis can lead to a significant improvement in the management of CVD and even to the development of novel efficient drugs. To note, over the last years, the observation that inflammation leads to atherosclerosis has gained interest providing a link between atheroma formation and oncogenesis. Here, we have focused on the description of the available therapy for atherosclerosis, including surgical treatment and experimental treatment, the mechanisms of atheroma formation, and possible novel therapeutic candidates such as the use of anti-inflammatory treatments to reduce CVD.

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“…Following publication of the original article [ 1 ], the authors would like to include two new co-authors and revised author’s contributions statement. Dr. Praveen Kerala Varma email: varmapk@gmail.com; praveenv21204@aims.amirta.edu Dr. Rajesh Jose email: rajeshj21304@aims.amirta.edu …”

Section: Correction To: Journal Of Nanobiotechnology (2022) 20:71 ...mentioning

confidence: 99%

Correction to: A novel small diameter nanotextile arterial graft is associated with surgical feasibility and safety and increased transmural endothelial ingrowth in pig

et al. 2022

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A novel small diameter nanotextile arterial graft is associated with surgical feasibility and safety and increased transmural endothelial ingrowth in pig

Cited by 6 publications

References 51 publications

Application of biomedical materials in the diagnosis and treatment of myocardial infarction

Application of biomedical materials in the diagnosis and treatment of myocardial infarction

Clinical implications of inflammation in atheroma formation and novel therapies in cardiovascular diseases

Correction to: A novel small diameter nanotextile arterial graft is associated with surgical feasibility and safety and increased transmural endothelial ingrowth in pig

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