A Novel Sensor for Sensitive and Selective Detection of Iodide Using Turn-on Fluorescence Graphene Quantum Dots/Ag Nanocomposite

Xu, Xianghong; Wang, Yanhui

doi:10.2116/analsci.31.787

Cited by 13 publications

(16 citation statements)

References 17 publications

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“…We investigated the capability of mechanically-treated carbon nanofibers (MCNF) as a promising platform for diagnosing both iodine deficiency (IDD) and iodine excess in urine. IDD is the most important preventable cause of neurological deficiencies worldwide and excess iodine can lead to thyroid-related disorders [ 2 , 6 ]. The unique microstructure and composition of MCNF electrodes make them uniquely suited for electrochemical sensing of iodine [ 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

“…Ideally, these methods should have fast response times, low limits of detection, a wide dynamic range, and capability of detecting iodide ions in the presence of interfering substances. Various nanomaterials, such as ZnO nanotubes-functionalized gold-coated glass, poly(3,4-ethylenedioxythiophene)/glassy carbon composite, plasticized polyvinyl chloride with two fluorescence, graphene quantum dots/silver nanocomposites, have been used for developing iodide sensors [ 6 , 7 , 8 , 9 ]. However, these sensing materials often use expensive precious metals such as gold or silver and require additional post fabrication chemical treatments or expensive optical setups to be effective sensors.…”

Section: Introductionmentioning

confidence: 99%

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Rapid Iodine Sensing on Mechanically Treated Carbon Nanofibers

Cho

Perebikovsky

Benice

et al. 2018

Sensors

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In this work, we report on a rapid, efficient electrochemical iodine sensor based on mechanically treated carbon nanofiber (MCNF) electrodes. The electrode’s highly graphitic content, unique microstructure, and the presence of nitrogen heteroatoms in its atomic lattice contribute to increased heterogeneous electron transfer and improved kinetics compared to conventional pyrolytic carbons. The electrode demonstrates selectivity for iodide ions in the presence of both interfering agents and high salt concentrations. The sensor exhibits clinically relevant limits of detection of 0.59 µM and 1.41 µM, in 1X PBS and synthetic urine, respectively, and a wide dynamic range between 5 µM and 700 µM. These results illustrate the advantages of the material’s unique electrochemical properties for iodide sensing, in addition to its simple, inexpensive fabrication. The reported iodine sensor eliminates the need for specimen processing, revealing its aptitude for applications in point-of-care diagnostics.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rapid Iodine Sensing on Mechanically Treated Carbon Nanofibers

Cho

Perebikovsky

Benice

et al. 2018

Sensors

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“…4 Interestingly, GQDs having the nano-scaled graphene structure exhibit both the properties of nanomaterials and desirable physical features of the other graphene-based structures, such as carboxylic acid functional groups and the π-π conjugated network. 5,6 The GQDs are usually in the size range of 3 -20 nm and have proven multivalent redox behavior in different sizes of 2.2 ± 0.3, 2.6 ± 0.2, and 3 ± 0.3, which can be recorded by voltammetry techniques and utilized for electrochemical sensing approaches. 7 Besides numerous reports of optical biosensors based on GQDs, electrochemical GQDs-modified biosensors have been recently reported, as it has been demonstrated that GQDs possess superior electron donor and acceptor capability compared to microsized graphene sheets along with a greater number of carboxyl groups and smaller dimensions compared to other carbon nanomaterials, such as graphene and carbon nanotubes.…”

Section: Introductionmentioning

confidence: 99%

Non-enzymatic Determination of L-Proline Amino Acid in Unprocessed Human Plasma Sample Using Hybrid of Graphene Quantum Dots Decorated with Gold Nanoparticles and Poly Cysteine: A Novel Signal Amplification Strategy

2018

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An innovative electrochemical interface for quantitation of L-proline (L-Pro) based on ternary amplification strategy was fabricated. In this work, gold nanoparticles prepared by soft template methodology were immobilized onto green and biocompatible nanocomposite containing poly as a conductive matrix and graphene quantum dots as the amplification element. Therefore, a novel multilayer film based on poly-L-cysteine, graphene quantum dots (GQDs), and gold nanoparticles (GNPs) was exploited to develop a highly sensitive electrochemical sensor for the detection of L-Pro. Fully electrochemical methodology was used to prepare a new transducer on a glassy carbon electrode, which provided a high surface area towards sensitive detection of L-Pro. The prepared electrode was employed for the detection of L-Pro. Under optimized conditions, the calibration curve for L-Pro concentration was linear in 0.5 nM - 10 mM with a low limit of quantification of 0.1 nM. The practical analytical utility of the modified electrode was illustrated by determination of L-Pro in unprocessed human plasma samples.

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“…Recently, photoluminescent nanocarbons, including carbon nanotubes, detonation diamonds 1 and graphene quantum dots (GQDs), 2 have received intensive attention concerning applications to analytical and biochemical research. 3 As an alternative to organic fluorophores 4 and toxic semiconductor quantum dots, 5 luminescent nanocarbons are superior in terms of chemical inertness, environmental suitability and stable photoluminescence (PL).…”

Section: Introductionmentioning

confidence: 99%

Effect of the Elemental Composition of Precursors from Amino Acids and Their Binary Mixtures on the Photoluminescent Intensity of Carbon Nanodots

et al. 2017

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Experimental ReagentsGlycine (Sigma Aldrich, ≥99%), L-glutamic acid (Sigma Aldrich, ≥99.0%), and L-cysteine (Sigma Aldrich, 97.0%) were used as received. 2-Morpholinoethanesulfonic acid monohydrate 2017 © The Japan Society for Analytical Chemistry † To whom correspondence should be addressed. E-mail: kotaro@sci.toho-u.ac.jp Effect of the Elemental Composition of Precursors from Amino Acids and Their Binary Mixtures on the Photoluminescent Intensity of Carbon NanodotsKotaro MORITA, † Shusei KURUSU, Haruka KODAMA, and Naoki HIRAYAMA Department of Chemistry, Faculty of Science, Toho University, 2-2-1 Miyama, Funabashi 274-8510, JapanWe report on the photoluminescent (PL) properties of carbon nanodots (CNDs) doped with nitrogen and sulfur obtained by the pyrolytic carbonization of amino acids as precursors. Prepared CNDs exhibit stable PL emission under a wide variety of aqueous conditions. The results also provided the way to tune a PL intensity of CNDs by varying the amount of heteroatoms in precursors with a binary mixture of amino acids. The PL quantum yields of the obtained CNDs were determined to be from 0.079 to 0.571.

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A Novel Sensor for Sensitive and Selective Detection of Iodide Using Turn-on Fluorescence Graphene Quantum Dots/Ag Nanocomposite

Cited by 13 publications

References 17 publications

Rapid Iodine Sensing on Mechanically Treated Carbon Nanofibers

Rapid Iodine Sensing on Mechanically Treated Carbon Nanofibers

Non-enzymatic Determination of L-Proline Amino Acid in Unprocessed Human Plasma Sample Using Hybrid of Graphene Quantum Dots Decorated with Gold Nanoparticles and Poly Cysteine: A Novel Signal Amplification Strategy

Effect of the Elemental Composition of Precursors from Amino Acids and Their Binary Mixtures on the Photoluminescent Intensity of Carbon Nanodots

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