A novel Schiff base cobalt(III) complex induces a synergistic effect on cervical cancer cells by arresting early apoptosis stage

Liao, Wei; Song, Xueqing; Kong, Yanjie; Bao, Rui-Dan; Li, Fangfang; Zhou, Jié; Zhao, Qi‐Hua; Xu, Jing‐Yuan; Xie, Ni; Xie, Ming‐Jin

doi:10.1007/s10534-020-00278-6

Cited by 6 publications

(3 citation statements)

References 38 publications

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“…Sci. 2021, 11, x FOR PEER REVIEW 10 .96 µ M (LoVo) IC50 = 22.68 µ M (A549) IC50 = 18.03 µ M (A549/cis) Liao et al (2021)[55]…”

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confidence: 99%

“…12.40 µM (HeLa) IC 50 = 18.96 µM (LoVo) IC 50 = 22.68 µM (A549) IC 50 = 18.03 µM (A549/cis) Liao et al (2021)[55] …”

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“…At 1 µ M kills 10% of HeLa cells Ö zdemir et al (2020) [57] 88 μM (Sk-Hep-1) IC50 = 8.28 μM (MHCC97-L) IC50 = 8.35 μM (NIH3T3) IC50 = 22.9 μM (MDA-MB-231) IC50 = 22.4 μM (A549) IC50 = 15.8 μM (A549/Taxol) Zhang et al (2021) [58] 33 At 1 µM kills 90% of HeLa cells Özdemir et al (2020) [57] .40 µ M (HeLa) IC50 = 18.96 µ M (LoVo) IC50 = 22.68 µ M (A549) IC50 = 18.03 µ M (A549/cis) Liao et al (2021)[55] …”

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confidence: 99%

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A Review on the Advancements in the Field of Metal Complexes with Schiff Bases as Antiproliferative Agents

et al. 2021

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Metal complexes play an essential role in pharmaceutical sciences for their multiple and important activities. Schiff bases are versatile pharmacophores able to form chelating complexes with several metals in different oxidation states. Complexes with Schiff bases are widely described in the literature for their multiple actions and numerous advantages, such as low cost and easy synthesis. They show multiple biological activities, including antimicrobial, antioxidant, antimalarial, antinflammatory and antitumor. Schiff bases may also form complexes with lanthanides and actinides acting as catalysts (e.g., in various synthetic processes) and antitumor agents. This review intends to extend on our previous paper regarding Schiff bases as antitumorals, highlighting the importance, in the field of the anticancer agents, of these tools as ligands of metal complexes.

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“…Sci. 2021, 11, x FOR PEER REVIEW 10 .96 µ M (LoVo) IC50 = 22.68 µ M (A549) IC50 = 18.03 µ M (A549/cis) Liao et al (2021)[55]…”

mentioning

confidence: 99%

“…12.40 µM (HeLa) IC 50 = 18.96 µM (LoVo) IC 50 = 22.68 µM (A549) IC 50 = 18.03 µM (A549/cis) Liao et al (2021)[55] …”

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mentioning

confidence: 99%

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A Review on the Advancements in the Field of Metal Complexes with Schiff Bases as Antiproliferative Agents

et al. 2021

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Novel indole Schiff base β-diiminato compound as an anti-cancer agent against triple-negative breast cancer: In vitro anticancer activity evaluation and in vivo acute toxicity study

Farghadani,

Lim,

Abdulla

et al. 2024

Bioorganic Chemistry

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Four acylhydrazone based complexes: Inhibition of proliferation, inducing apoptosis and inhibiting cell migration

Zong,

Zhou,

Chang

et al. 2024

Journal of Molecular Structure

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A novel Schiff base cobalt(III) complex induces a synergistic effect on cervical cancer cells by arresting early apoptosis stage

Cited by 6 publications

References 38 publications

A Review on the Advancements in the Field of Metal Complexes with Schiff Bases as Antiproliferative Agents

A Review on the Advancements in the Field of Metal Complexes with Schiff Bases as Antiproliferative Agents

Novel indole Schiff base β-diiminato compound as an anti-cancer agent against triple-negative breast cancer: In vitro anticancer activity evaluation and in vivo acute toxicity study

Four acylhydrazone based complexes: Inhibition of proliferation, inducing apoptosis and inhibiting cell migration

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