A novel ratiometric electrochemical sensor based on dual-monomer molecularly imprinted polymer and Pt/Co3O4 for sensitive detection of chlorpromazine hydrochloride

An electrochemical chlorpromazine sensor based on a gold–copper bimetallic synergetic molecularly imprinted interface on an acupuncture needle electrode

“…Chlorpromazine (CPZ) is a phenothiazine derivative 1,2 and is widely used to regulate the tension and anxiety states of schizophrenia patients 3 and treat various mental diseases due to its unique central inhibitory effect. 4 The in vivo detection of CPZ is of great significance.…”

A novel electrochemical sensing platform based on the esterase extracted from kidney bean for high-sensitivity determination of organophosphorus pesticides

“…30,37 The limit of detection (LOD) is an important index to evaluate the sensitivity, which can be calculated by the following equation. 38–40 LOD = kS b / S where S b is the standard deviation of multiple measurements of the blank system; S is the slope of the calibration curve in the low concentration range; k is a coefficient related to the confidence level, and IUPAC recommends to be 3. The calculated LOD is as low as 3 ng L −1 .…”

Recent Advances of Nanomaterials-Based Molecularly Imprinted Electrochemical Sensors

“…In tests of environmental samples, the sensors showed an ultra-low LOD (0.078 nM). Liu et al [ 64 ] constructed a novel sensor by electrodepositing a dual-monomer MIP film on the electrode with Pt/Co 3 O 4 nanoparticles modification. These transition metal oxides supported by noble-metal catalysts had a good catalytic activity and large surface area to enhance the detection sensitivity of the sensor.…”