A novel ratiometric and reversible fluorescent probe based on naphthalimide for the detection of Al³⁺ and pH with excellent selectivity

Abstract

A novel ratiometric and reversible fluorescence probe was designed and synthesized. The fluorescent probe recognizes Al3+ to cause a blue shift in the fluorescence emission spectrum. Fluorescence probe can be used as a sensor to detect Al3+ in living cells and Zebra fishes. The probe can detect the pH value when the alkalinity range was 8–10.

A Highly Selective Fluorescent Probe for Hg2+ Based on a 1,8-Naphthalimide Derivative

“…Naphthalimide and its derivatives have been extensively applied in optical sensing owing to their favorable spectroscopic properties including superior light stability, high luminescence efficiency, and large Stokes shifts. − Recently, naphthalimide-based probes have been reported to detect various substances including Hg 2+ , − Zn 2+ , Cu 2+ , Ag + , , Cd 2+ , Pd 2+ , Al 3+ , Cr 3+ , glutathione S-transferase, and endoplasmic reticulum aminopeptidase 1 . However, some of these naphthalimide-based fluorescent probes for Hg 2+ were constructed by utilizing the fluorescence quenching mechanism and their sensitivity was poor. , In this article, a novel turn-on Hg 2+ fluorescent probe 1 has been developed with a naphthalimide group (Scheme ).…”

A fluorescent nanoprobe based on AIEgen: Visualization of silver ions and sensing applications in cancer cells and S. aureus

“…Many fluorescence-based molecular probes were reported to detect silver ions. However, some limitations still remained such as [19][20][21][22][23][24], low selectivity [19,20], low sensitivity [20,24], no various application [9,22,24] (Table S1) and it is significant challenging to design a turn-on type fluorescent probe due to the fluorescence quenching property of silver ions toward fluorophore from the charge transfer process; thus, most reported probes used a turn-off response instead.…”

“…The MTA moiety could be conjugated to fluorophores via imine bond formation (Type 1) or secondary amine bond (Type 2), and it could sense a specific metal ion such as copper (II) ions (Cu 2+ ), zinc (II) ions (Zn 2+ ), mercury (II) ions (Hg 2+ ), and aluminum (III) ions (Al 3+ ) by forming a coordinate covalent bond with metal ions between nitrogen and sulfur atoms within its structure (Fig. 1a) [19][20][21][22][23][24]. The metal ion sensing mechanism of MTA moiety depends on whether it forms an imine bond or secondary amine bond combined with a fluorophore.…”

Preparation and properties of a novel polystyrene solid-phase fluorescence pH sensor based on a naphthalimide derivative

“…This property favored PET quenching of the excited state of the naphthalimide by electron-rich receptors located at the 4-position. [15][16][17][18] Based on this property, several naphthalimide-based sensors have been reported to detect various ions, including Hg 2+ , 13,19 Cu 2+ , 20 Zn 2+ , 21 Ag + , 22 Pd 2+ , 23 Cd 2+ , 24 Al 3+ , 25 and Cr 3+ . 26 The pH-sensitive naphthalimide derivatives were immobilized on the outer surface of rhodamine-doped silica nanoparticles, gel, TentaGel MB NH 2 , by Trupp and Matthew groups, respectively.…”