A Novel Radial Artery P-S Curve Model Based on Radial Vibration of Vascular Wall

Abstract

In pulse wave analysis, the changing curve of pulse wave strength with continuous increasing pressure, that is, the P-S (pressure-strength) curve, contains abundant human physiological information, but there is no accurate model to describe the formation mechanism of the curve. Therefore, this paper proposes a modeling method of the radial artery P-S curve based on the radial vibration of the vascular wall. The modeling method includes three parts. Firstly, based on hemodynamics, we proposed the blood motion equation in the pulsation process of healthy people. Secondly, the motion equation of the vascular wall based on the fluid–structure interaction between blood motion and vascular wall was established. Finally, according to the elastic theory of the vascular wall, the relationship between pulse strength and extravascular pressure of blood vessels was found. To verify the accuracy and applicability of the model, this paper simulated the changes in the vascular wall stress and the intravascular pressure with the extravascular pressure during the process of vascular deformation. In addition, 69 healthy volunteers were selected to participate in this study. Based on the gradient compression, the pulse strength envelope under the continuous pressure sequence of the radial artery, namely the pulse P-S curve, was extracted. We also analyzed the relationship between the individual P-S curve difference and BMI. The results show that the actual human body data collection and analysis results are consistent with the theoretical model established in this paper, which indicates that the model can provide a novel idea for the evaluation of the state of the human body.

Wearable Multi-Channel Pulse Signal Acquisition System Based on Flexible MEMS Sensor Arrays with TSV Structure

“…This was achieved using bicubic interpolation, which concatenated the pulse wave intensities from each sensor and created a pulse wave intensity mapping surface for cubic interpolation in the X and Y directions. The smooth 3D pulse wave is shown in Figure 5 c. The pulse intensity along the radial artery was stronger than that around, which was consistent with existing studies [ 4 , 14 ]. The 3D pulse wave was more in line with the pulse diagnosis finger feeling of a TCM doctor.…”

“…The smooth 3D pulse wave is shown in Figure 5c. The pulse intensity along the radial artery was stronger than that around, which was consistent with existing studies [4,14]. The 3D pulse wave was more in line with the pulse diagnosis finger feeling of a TCM doctor.…”

“…Studies have shown that pulse waves contain adequate information reflecting the state of the human heart and blood vessels [ 1 , 2 ]. This information can be utilized to predict and reflect a variety of cardiovascular disease states in clinical TCM practice, such as hypertension [ 3 ], coronary heart disease [ 4 , 5 ], arterial stiffness [ 6 ], vascular aging [ 7 ], and atrial fibrillation [ 8 ]. Given its non-invasive, convenient, and rapid diagnosis, pulse diagnosis has significant potential for application and development.…”

Application of translation wavelet transform with new threshold function in pulse wave signal denoising

“…The best pulse wave band is obtained by extracting the pulse wave at the strongest point of the D-S curve. Since the signal is stable, the optimal pulse wave band is of great significance in the intelligent diagnosis of traditional Chinese medicine, which is also the pulse wave band that this paper mainly deals with [24]. The hard threshold function and soft threshold function's schematic diagrams are shown in Fig.…”