A novel quorum sensing regulator LuxT contributes to the virulence of
Vibrio cholerae
Yuehua Li,
Junxiang Yan,
Jinghao Li
et al.
Abstract:Vibrio cholerae
is a waterborne bacterium that primarily infects the human intestine and causes cholera fatality. Quorum sensing (QS) negatively regulates the expression of
V. cholerae
virulence gene. However, the primary associated mechanisms remain undetermined. This investigation identified a new QS regulator from the TetR family, LuxT, which increases
V. cholerae
virulence by directly inhibiting
hapR
expression. HapR is a maste… Show more
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