A Novel Presentation of Clostridium perfringens in Young Broilers

Thiemann, Rachel; Thornton, Jay Kay; Stayer, Philip A.; Riley, Erin P.; Clark, Randi; Armour, Natalie; Pulido-Landínez, Martha

doi:10.1637/aviandiseases-d-21-00107

Cited by 3 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nonetheless, this could also be an example that this bacterium is changing its presentation Enterococci are known to be intrinsically resistant to several antimicrobial agents. Whereas this has been widely investigated in other enterococcal species such as E. faecalis and E. faecium, less is known for E. cecorum (8). In prior studies, pathogenic E. cecorum isolates have shown resistance to a broad range of antibiotics (6).…”

Section: Discussionmentioning

confidence: 99%

“…Hierarchical clustering organization. Once E. cecorum was identified, research-use only SARAMIS software (10) was used to create a hierarchical clustering of E. cecorum isolates (Super Spectra; [SS]), comparing their mass spectrometric patterns and analyzing their relative taxonomy following the methodology established by Thiemann et al in 2022 (8). Isolates with 90 or more detected masses were included in this analysis.…”

Section: Methodsmentioning

confidence: 99%

“…Each suspected culture was tested in duplicate to minimize the effect of variations due to potential mixed cultures. For instrument calibration, Escherichia coli ATCC 8739 was included with every 16 samples (8).…”

Section: Data Collection An Accession List Was Built From the Poultrymentioning

confidence: 99%

See 2 more Smart Citations

Characterization of an Emerging Enterococcus cecorum Outbreak Causing Severe Systemic Disease with Concurrent Leg Problems in a Broiler Integrator in the Southern United States

2023

Self Cite

View full text Add to dashboard Cite

Enterococcus cecorum has been associated mainly with osteomyelitis of the free thoracic vertebra in chickens. However, there are reports of E. cecorum producing septicemic lesions and having tropism for cartilages, resulting in the presentation of femoral head necrosis and synovitis. This paper discusses the presentation of E. cecorum as it relates to an outbreak in one vertical integrator where the main lesions were related to septicemia. Using a convenience sampling method, 100 broiler chicken cases received at the Poultry Research and Diagnostic Laboratory of Mississippi State University from April to December of 2021 were analyzed. The peak in cases was observed from June to August. The average age of broilers was 21 days with a range of 15-31 days. Most of these cases were related to systemic disease and leg problems, with gross lesions including characteristic pericarditis along with perihepatitis, osteomyelitis, and arthritis. In six of the 100 cases, E cecorum was isolated from the free thoracic vertebra, with the remaining being recovered from various other locations including liver, pericardium, hock/joint, femoral head, and bone marrow. Enterococcus cecorum identification was performed by using Vitek matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. These results were then sent to the research-use only SARAMIS database for analysis. Once the spectra of the isolates were imported, the relative and absolute taxonomy were analyzed. Two super spectrums and three clusters by homology were identified. The minimal inhibitory concentrations obtained by antimicrobial sensitivity tests were analyzed using WHONET Microbiology Laboratory Database Software. No isolates were pan-susceptible, 80% of isolates were noted to be resistant to 3 classes of antibiotics and, in general, isolates exhibited a high degree of variability when examining antimicrobial resistance patterns.RESUMEN. Reporte de caso-Caracterización de un brote reciente de Enterococcus cecorum causante de una enfermedad sistémica grave simulta ´neamente con problemas en las patas en un integrador de pollo de engorde en el sur de los Estados Unidos.La bacteria Enterococcus cecorum se ha asociado principalmente con osteomielitis de la vértebra tora ´cica móvil de los pollos. Sin embargo, existen reportes de E. cecorum produciendo lesiones septicémicas y presentando tropismo por los cartílagos, resultando en la presentación de necrosis de la cabeza femoral y sinovitis. Este artículo analiza la presentación de E. cecorum relacionada con un brote en un integrador vertical donde las principales lesiones estaban relacionadas con septicemia. Utilizando un método de muestreo de conveniencia, se analizaron 100 casos de

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Characterization of an Emerging Enterococcus cecorum Outbreak Causing Severe Systemic Disease with Concurrent Leg Problems in a Broiler Integrator in the Southern United States

2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…The study conducted by Thiemann et al [45] involves analyzing the genomes, physiology, and morphology of animals from multiple generations that have been exposed to controlled gamma, x-ray, or ion beam irradiation. The purpose of this study is to understand the rates of mutations and the mechanisms of adaption.…”

Section: Environmental Monitoringmentioning

confidence: 99%

Introductory chapter: Exploring the Multifaceted Applications of Gamma Rays in Science and Technology

M. Saleh,

I. Hassan

2024

Gamma Rays - Current Insights

View full text Add to dashboard Cite

“…Chronic NE can cause loss of appetite, reduced intestinal absorption, a lowered feed conversion rate, and weight loss, leading to a reduction in poultry performance. Acute NE can cause sudden and massive death of poultry, with features such as inflammation, multifocal, irregular, plaque-like mucosal ulcers, and necrosis in the upper part of the small intestine after dissection [ 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Bacillus amyloliquefaciens SC06 on Behavior and Brain Function in Broilers Infected by Clostridium perfringens

Chen,

Liu,

Luo

et al. 2024

Animals

View full text Add to dashboard Cite

Poultry studies conducted on Clostridium perfringens (CP) mainly focus on the effects of intestinal health and productive performance. Notably, the probiotic Bacillus amyloliquefaciens SC06 (BaSC06) is known to play a role in preventing bacterial infection. However, whether CP could induce the changes in brain function and behaviors and whether BaSC06 could play roles in these parameters is yet to be reported. The aim of this study was to evaluate the effects of BaSC06 on stress-related behaviors and gene expression, as well as the brain morphology and mRNA sequence of the hypothalamus in broiler chickens. A total of 288 one-day-old chicks were randomly divided into four groups: (1) a control group with no treatment administered or infection; (2) birds treated with the BaSC06 group; (3) a CP group; and (4) a BaSC06 plus CP (Ba_CP) group. The results showed that stress and fear-related behaviors were significantly induced by a CP infection and decreased due to the treatment of BaSC06. CP infection caused pathological damage to the pia and cortex of the brain, while BaSC06 showed a protective effect. CP significantly inhibited hypothalamic GABA and promoted HTR1A gene expression, while BaSC06 promoted GABA and decreased HTR1A gene expression. The different genes were nearly found between the comparisons of control vs. Ba group and Ba vs. CP group, while there were a great number of different genes between the comparisons of control vs. Ba_CP as well as CP vs. Ba_CP. Several different gene expression pathways were found that were related to disease, energy metabolism, and nervous system development. Our results will help to promote poultry welfare and health, as well as provide insights into probiotics to replace antibiotics and reduce resistance in the chicken industry.

show abstract

A Novel Presentation of Clostridium perfringens in Young Broilers

Cited by 3 publications

References 25 publications

Characterization of an Emerging Enterococcus cecorum Outbreak Causing Severe Systemic Disease with Concurrent Leg Problems in a Broiler Integrator in the Southern United States

Characterization of an Emerging Enterococcus cecorum Outbreak Causing Severe Systemic Disease with Concurrent Leg Problems in a Broiler Integrator in the Southern United States

Introductory chapter: Exploring the Multifaceted Applications of Gamma Rays in Science and Technology

The Effects of Bacillus amyloliquefaciens SC06 on Behavior and Brain Function in Broilers Infected by Clostridium perfringens

Contact Info

Product

Resources

About