A novel optical biosensor for direct and selective determination of serotonin in serum by Solid Surface-Room Temperature Phosphorescence

Ramón‐Márquez, Teresa; Medina-Castillo, Antonio L.; Gutiérrez, Alberto Fernández

doi:10.1016/j.bios.2016.04.008

Cited by 34 publications

(10 citation statements)

References 67 publications

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“…Many proteins in living organisms and algae in polluted water have strong fluorescence emissions, leading to the failure of the fluorescent probe. Phosphorescent detection avoids interference from the short-lifetime fluorescent background or scattered light in real samples 50 , providing a higher sensitivity and signal-to-noise ratio of detection in complicated media. Taking advantage of the long-lived persistent RTP in aqueous media, the CD-CA suspension could be utilised as a sensor for the detection of metal ions in water.…”

Section: Resultsmentioning

confidence: 99%

Induction of long-lived room temperature phosphorescence of carbon dots by water in hydrogen-bonded matrices

et al. 2018

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Phosphorescence shows great potential for application in bioimaging and ion detection because of its long-lived luminescence and high signal-to-noise ratio, but establishing phosphorescence emission in aqueous environments remains a challenge. Herein, we present a general design strategy that effectively promotes phosphorescence by utilising water molecules to construct hydrogen-bonded networks between carbon dots (CDs) and cyanuric acid (CA). Interestingly, water molecules not only cause no phosphorescence quenching but also greatly enhance the phosphorescence emission. This enhancement behaviour can be explained by the fact that the highly ordered bound water on the CA particle surface can construct robust bridge-like hydrogen-bonded networks between the CDs and CA, which not only effectively rigidifies the C=O bonds of the CDs but also greatly enhances the rigidity of the entire system. In addition, the CD-CA suspension exhibits a high phosphorescence lifetime (687 ms) and is successfully applied in ion detection based on its visible phosphorescence.

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Section: Resultsmentioning

confidence: 99%

Induction of long-lived room temperature phosphorescence of carbon dots by water in hydrogen-bonded matrices

et al. 2018

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“…Mimicking collagen nanofibers diameters have been shown to enhance cell attachment on tissues about 1.7 fold [21]. Even when specific studies of cell adhesion and proliferation need to be conducted, the hydrophilicity of tested surfaces [22], and nanoroughness are important parameters that will promote protein non-specific adhesion and cellular attachment to proposed matrices [7,21].…”

Section: Discussionmentioning

confidence: 99%

Novel potential scaffold for periodontal tissue engineering

et al. 2017

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“…The results demonstrate the ability of the biosensor to rapidly and qualitatively determine the presence of adrenaline (at approximately 1nM) using the Boolean logic-gate principle. Another report of Molinnuset al 43 in the literature also described an amperometric enzymatic biosensor to detect adrenaline. This one was prepared by means of an oxygen electrode withlaccase operating between 3.5 and 8.0 pH range.…”

Section: Indirect Diagnosis Of Fmmentioning

confidence: 98%

A mini review on the use of biosensors for indirectly assisting the diagnosis of fibromyalgia

Faria¹,

Silva²

2020

IJBSBE

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Fibromyalgia (FM) is a syndrome known mainly for causing muscular and skeletal pain, whose etiology still remains unknown. Besides intense pain, FM patients can also present a clinical picture of fatigue, insomnia, headaches and intestinal changes. One of the most important challenges related to the disease is the difficult diagnosis, which can be confusing because it presents symptoms common in many other pathologies (like anxiety and depression). Some characteristics that can contribute to a better diagnosis are the differences in the level of certain biological molecules, such as some hormones and markers. The conversion of the information referring to the levels of these biological compounds into a measurable analytical signal is the focus of some biosensors recently reported in the literature. These devices are expected to collaborate in increasing the reliability of the indirect FM diagnostics. In this sense, this mini review presents an overview on the recent trends on the fabrication of some biosensors based on different transduction mechanisms and bioreceptors to detect analytes of interest for the indirect diagnosis of FM.

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A novel optical biosensor for direct and selective determination of serotonin in serum by Solid Surface-Room Temperature Phosphorescence

Cited by 34 publications

References 67 publications

Induction of long-lived room temperature phosphorescence of carbon dots by water in hydrogen-bonded matrices

Induction of long-lived room temperature phosphorescence of carbon dots by water in hydrogen-bonded matrices

Novel potential scaffold for periodontal tissue engineering

A mini review on the use of biosensors for indirectly assisting the diagnosis of fibromyalgia

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