Abstract:VWD is reported as the most common inherited bleeding disorder worldwide, found in approximately 1% population [1-4]. It can be divided into 3 subtypes: type 1, type 2 and type 3, caused by quantitative or qualitative defects of VWF. VWF is a complex plasma protein essential for primary hemostasis and coagulation. VWF helps to bind and stabilize blood clotting FVIII from rapid breakdown within the blood stream. Any defect in VWF can also cause reduction of FVIII levels [5]. Type 3 VWD is the rarest and most s… Show more
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