A novel molecular mechanism of action for azathioprine in IBD: 6-Thio-GTP induces apoptosis of lamina propria T cells via blockade of the GTPase Rac1

Tiede, Imke; Poppe, Daniela; Strand, Susanne; Strand, Dennis; Wirtz, Stefan; Becker, Christoph; Blumberg, Richard S.; Iven, H.; Ahmadian, Reza; Galle, Peter R.; Neurath, Markus F.

doi:10.1016/s0016-5085(03)81616-5

Gastroenterology

2003

DOI: 10.1016/s0016-5085(03)81616-5

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A novel molecular mechanism of action for azathioprine in IBD: 6-Thio-GTP induces apoptosis of lamina propria T cells via blockade of the GTPase Rac1

Imke Tiede¹,

Daniela Poppe²,

Susanne Strand³

et al.

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A novel molecular mechanism of action for azathioprine in IBD: 6-Thio-GTP induces apoptosis of lamina propria T cells via blockade of the GTPase Rac1

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