Abstract:Introduction:Haemophilia A is the most common inherited X-linked recessive bleeding disorder. The severity of the resultant bleeding diathesis depends on the FVIII levels associated with the mutation. Analysis of carrier state can be made indirectly by DNA linkage analysis or directly by identifying the mutation that leads to the disease. The aim of this study was to identification of the causal mutation of the FVIII gene in a haemophilic patient.Case Report:Our case is a 16-year-old male haemophilia A patient… Show more
“…22 Other studies have been distributed in different parts of the country; a number of them were performed for carrier detection with simple and less expensive methods. [25][26][27][28][29] As with HA, molecular studies on HB patients have been rarely performed. Only a small number of Iranian patients were analyzed for underlying gene defects.…”
Section: Diagnosis Of Hemophilia In Iranmentioning
Although this study was performed in Iranian patients, the large number thereof gives confidence that the results can be used more widely for other countries, especially in the developing world.
“…22 Other studies have been distributed in different parts of the country; a number of them were performed for carrier detection with simple and less expensive methods. [25][26][27][28][29] As with HA, molecular studies on HB patients have been rarely performed. Only a small number of Iranian patients were analyzed for underlying gene defects.…”
Section: Diagnosis Of Hemophilia In Iranmentioning
Although this study was performed in Iranian patients, the large number thereof gives confidence that the results can be used more widely for other countries, especially in the developing world.
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