A Novel Minimally Invasive Surgically Induced Skeletal Muscle Injury Model in Sheep
Laura Vidal,
Ingrid Vila,
Vanesa Venegas
et al.
Abstract:Sports-related muscle injuries account for 10–55% of all injuries, which is a growing concern, especially given the aging world population. To evaluate the process of skeletal muscle injury and compare it with muscle lesions observed in humans, we developed a novel in vivo model in sheep. In this model, muscle injury was induced by an ultrasound-guided transverse biopsy at the myotendinous junction of the medial gastrocnemius muscle. Twelve male sheep were examined at 3, 7, 14, and 28 days post-injury. Histolo… Show more
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