Abstract:1The meiotic spindle in oocytes is assembled in the absence of centrosomes, the major 2 microtubule nucleation sites in mitotic and male meiotic cells. A crucial, yet unresolved 3 question in meiosis is how spindle microtubules are generated without centrosomes and 4 only around chromosomes in the large volume of oocytes. Here we report a novel oocyte-5 specific microtubule nucleation pathway that is essential for assembling most spindle 6 microtubules complementarily with the Augmin pathway, and sufficient fo… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.